"The Fed doesn't have a clue," Trump tweeted Tuesday as U.S. policymakers began the first of a two day meeting.
He was responding to a FOX Business "Varney & Co." segment that discussed negative central bank interest rates in Europe and Japan.
Trump said U.S. central bank officials should follow their lead.
"The Fed doesn't have a clue! We have unlimited potential, only held back by the Federal Reserve. But we are winning anyway!"
A decision on interest rates will come Wednesday after the bank's seventh policy meeting of 2019. Observers expect the Fed to cut the target rate by 25 basis points, to a range of 1.50 percent to 1.75 percent.