| Date | Name | Shares | Transaction | Value |
|
Mar 18, 2026
| Carmen Bozic EVP and CMO |
35,405
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $481.79 per share |
17,057,774.95
|
|
Mar 3, 2026
| Kristin Ambrose SVP & Chief Accounting Officer |
6,624
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $483.36 per share |
3,201,776.64
|
|
Feb 20, 2026
| Nia Tatsis EVP, Chief Reg. & Quality Off. |
49,018
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $489.46 per share |
23,992,350.28
|
|
Feb 20, 2026
| Nia Tatsis EVP, Chief Reg. & Quality Off. |
49,627
| Payment of exercise price or tax liability by delivering/withholding secs incident to the receipt/exercise/vesting pursuant to Rule 16b-3 Non-derivative transaction at $483.75 per share |
24,007,061.25
|
|
Feb 20, 2026
| Nia Tatsis EVP, Chief Reg. & Quality Off. |
51,921
| Grant, award or other acq pursuant to Rule 16b-3(d) |
0.00
|
|
Feb 20, 2026
| Jonathan Prim Biller EVP and Chief Legal Officer |
15,748
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $473.68 per share |
7,459,512.64
|
|
Feb 20, 2026
| Jonathan Prim Biller EVP and Chief Legal Officer |
16,992
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $489.46 per share |
8,316,904.32
|
|
Feb 20, 2026
| Jonathan Prim Biller EVP and Chief Legal Officer |
19,468
| Payment of exercise price or tax liability by delivering/withholding secs incident to the receipt/exercise/vesting pursuant to Rule 16b-3 Non-derivative transaction at $483.75 per share |
9,417,645.00
|
|
Feb 20, 2026
| Jonathan Prim Biller EVP and Chief Legal Officer |
20,973
| Grant, award or other acq pursuant to Rule 16b-3(d) |
0.00
|
|
Feb 20, 2026
| Reshma Kewalramani CEO & President; Director |
143,259
| Payment of exercise price or tax liability by delivering/withholding secs incident to the receipt/exercise/vesting pursuant to Rule 16b-3 Non-derivative transaction at $483.75 per share |
69,301,541.25
|
|
Feb 20, 2026
| Reshma Kewalramani CEO & President; Director |
149,813
| Grant, award or other acq pursuant to Rule 16b-3(d) |
0.00
|
|
Feb 20, 2026
| Carmen Bozic EVP and CMO |
41,516
| Payment of exercise price or tax liability by delivering/withholding secs incident to the receipt/exercise/vesting pursuant to Rule 16b-3 Non-derivative transaction at $483.75 per share |
20,083,365.00
|
|
Feb 20, 2026
| Charles F. Wagner EVP, CO & FO |
51,080
| Grant, award or other acq pursuant to Rule 16b-3(d) |
0.00
|
|
Feb 20, 2026
| Amit K. Sachdev EVP Chief Patient & Ext Af Off |
69,042
| Payment of exercise price or tax liability by delivering/withholding secs incident to the receipt/exercise/vesting pursuant to Rule 16b-3 Non-derivative transaction at $483.75 per share |
33,399,067.50
|
|
Feb 20, 2026
| Amit K. Sachdev EVP Chief Patient & Ext Af Off |
71,182
| Grant, award or other acq pursuant to Rule 16b-3(d) |
0.00
|
|
Feb 20, 2026
| Kristin Ambrose SVP & Chief Accounting Officer |
9,945
| Payment of exercise price or tax liability by delivering/withholding secs incident to the receipt/exercise/vesting pursuant to Rule 16b-3 Non-derivative transaction at $483.75 per share |
4,810,893.75
|
|
Feb 20, 2026
| Duncan J. McKechnie EVP, Chief Commercial Officer |
23,342
| Payment of exercise price or tax liability by delivering/withholding secs incident to the receipt/exercise/vesting pursuant to Rule 16b-3 Non-derivative transaction at $483.75 per share |
11,291,692.50
|
|
Feb 20, 2026
| Nia Tatsis EVP, Chief Reg. & Quality Off. |
48,650
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $473.68 per share |
23,044,532.00
|
|
Feb 20, 2026
| Jeffrey M. Leiden Executive Chairman; Director |
38,344
| Payment of exercise price or tax liability by delivering/withholding secs incident to the receipt/exercise/vesting pursuant to Rule 16b-3 Non-derivative transaction at $483.75 per share |
18,548,910.00
|
|
Feb 20, 2026
| Jeffrey M. Leiden Executive Chairman; Director |
41,308
| Grant, award or other acq pursuant to Rule 16b-3(d) |
0.00
|