Why Sorrento Therapeutics Is Jumping Today
What happened
Shares of Sorrento Therapeutics (NASDAQ: SRNE) were jumping by 6.2% as of 11:40 a.m. EST on Wednesday after spiking as much as 14.9% earlier in the day. The clinical-stage biotech announced encouraging results from a discovery study that evaluated the potential of experimental drug resiniferatoxin (RTX) in treating Parkinson's disease.
So what
Sorrento didn't really have high hopes for RTX in Parkinson's disease. However, the company's lab study found that mice who received an injection of RTX experienced a notable improvement in motor function. No significant adverse effects were observed in the mice.
Both Sorrento and investors were pleased with the unexpectedly positive results. Sorrento CEO Henry Ji stated:
But it's still very early before it will be known if RTX truly has potential in helping Parkinson's disease patients. In addition, Sorrento specifically noted that there weren't significant effects on dopamine levels in the mice that were injected with RTX. That's surprising since the loss of dopamine in the brain causes issues with motor function in Parkinson's disease patients.
Sorrento thinks that this lack of change in dopamine levels could mean that the improved motor function in the mice was caused by factors other than direct protection of what are known as nigrostriatal dopaminergic neurons. The company suspects that RTX could be modulating neuroinflammation and/or relieving pain, thereby improving motor function.
Now what
Sorrento plans to publish the full results of the discovery study in a major scientific journal later this year. In addition, the company will present the data at an upcoming neurosciences conference.
In the meantime, Sorrento will keep moving forward with preclinical work for RTX. The company's goal is to file for Food and Drug Administration approval for the initiation of a phase 1 clinical study by the end of 2019.
10 stocks we like better than Sorrento TherapeuticsWhen investing geniuses David and Tom Gardner have a stock tip, it can pay to listen. After all, the newsletter they have run for over a decade, Motley Fool Stock Advisor, has quadrupled the market.*
David and Tom just revealed what they believe are the ten best stocks for investors to buy right now... and Sorrento Therapeutics wasn't one of them! That's right -- they think these 10 stocks are even better buys.
*Stock Advisor returns as of March 1, 2019
Keith Speights has no position in any of the stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.