Meadowbrook, NephroGenex, Chevron, RedHill Biopharma and Tekmira are big market movers

Stocks that moved substantially or traded heavily Wednesday on the New York Stock Exchange and the Nasdaq Stock Market:

NYSE

Meadowbrook Insurance Group Inc. (MIG), up $1.33 to $8.46

China's Fosun International investment group will buy the commercial insurance underwriter at a premium for about $433 million.

Chevron Corp. (CVX), down 93 cents to $112.18

The price of crude oil continued its months-long decline on weak demand, weighing down shares of the energy company and its peers.

Resolute Energy Corp. (REN), up 28 cents to $1.32

The oil and gas company said it secured a term loan for $150 million and that it amended its senior revolving credit facility.

Civeo Corp. (CVEO), up 19 cents to $4.11

The workforce accommodations company's stock rebounded a day after it provided a weak outlook and suspended its dividend.

Nasdaq

NephroGenex Inc. (NRX), up $8.31 to $12.96

The pharmaceutical company announced a successful completion of a cardiac safety study for a potential kidney disease treatment.

RedHill Biopharma Ltd. (RDHL), up $2.68 to $13.41

The biotechnology company's potential treatment for chemotherapy side-effects was accepted for review in the United Kingdom.

Aquinox Pharmaceuticals Inc. (AQXP), up 26 cents to $7.51

The pharmaceutical company started dosing patients in a midstage clinical trial focusing on a potential skin disorder treatment.

Tekmira Pharmaceuticals Corp. (TKMR), up $1.24 to $15.14

The drug developer said it completed enrollment in clinical studies focusing on a potential treatment for a group of cancers.