Amazon says it’s 'working closely' with authorities after cargo plane crash kills 5

At least five people were killed, and five others were injured in the crash

Amazon said it is cooperating with authorities after a cargo plane operating on behalf of Amazon Air crashed while attempting to land at Miami International Airport on Sunday, killing at least five people and injuring five others.

The company confirmed to FOX Business that the aircraft involved in the crash was operated by cargo carrier 21 Air, which flies for Amazon Air. 

Amazon Air is Amazon's air cargo network, helping move packages between the company's facilities, according to its website.

"We're heartbroken to learn that five people lost their lives in today’s incident at Miami International Airport. Our deepest sympathies go out to the families, loved ones, and all those affected by this devastating loss," an Amazon spokesperson said.

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An Amazon cargo plane is seen crashed

An Amazon cargo plane is seen after it crashed at Miami International Airport on September 6, 2026, in Miami, Florida.  (Joe Raedle/Getty Images)

"The airplane, which was operated by 21 Air, was attempting to land when this incident occurred. We're working closely with local authorities and officials to learn more and will cooperate fully with any investigation," the spokesperson added.

Prime Air Flight 7598 — a Boeing 767-300 operated by 21 Air — overran the runway while attempting to land at Miami International Airport around 2 p.m. local time after departing San Juan, Puerto Rico, according to authorities.

Miami-Dade officials said the aircraft struck multiple vehicles and caught fire

At least five people were killed, and five others were injured. Three victims were transported to a trauma center in critical condition, while two others were taken to a local hospital, authorities said.

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The airplane tail of a cargo plane that says Amazon

Prime Air Flight 7598 overran the runway while attempting to land at Miami International Airport around 2 p.m. local time after departing San Juan, Puerto Rico. (CHANDAN KHANNA / AFP via Getty Images)

The Federal Aviation Administration (FAA) and National Transportation Safety Board (NTSB) are investigating the crash.

Boeing told Fox News that the aircraft was first delivered as a passenger plane in 1994 before later being converted to a freighter.

"Boeing extends our deepest condolences to the families and loved ones of those who lost their lives in the accident in Miami," the company said.

"Our hearts go out to those injured and affected by this tragedy. Boeing is supporting the investigation led by the U.S. National Transportation Safety Board."

It was not immediately clear whether the crash would affect Amazon Air operations or package deliveries.

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The Amazon logo

It was not immediately clear whether the crash would affect Amazon Air operations or package deliveries. (KAZUHIRO NOGI/AFP via Getty Images)

Previous cargo aircraft accidents have prompted heightened regulatory scrutiny and, in certain cases, resulted in temporary operational disruptions. 

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The last fatal crash involving Amazon's air cargo network occurred in 2019, when an Atlas Air Boeing 767 operating for Amazon Air crashed in Texas, killing all three people aboard, officials said at the time.

21 Air could not immediately be reached by FOX Business for comment.

Fox News Digital's Bonny Chu contributed to this report.