AbbVie, Shire, Bank of America, Lakeland Industries and Petrobras are big market movers

Stocks that moved substantially or traded heavily Wednesday on the New York Stock Exchange and the Nasdaq Stock Market:


AbbVie Inc., up 50 cents to $54.63

The pharmaceutical company is reconsidering its $55 billion buyout of Shire, putting it at risk of paying a $1.6 billion fee.

Bank of America Corp., down 76 cents to $15.76

The bank reported a drop in quarterly profit because of a settlement over mortgage-backed securities with the U.S. government.

KeyCorp, down 75 cents to $12.14

The regional bank reported a decline in third-quarter profit and revenue, which fell short of Wall Street expectations.

Petrobras SA, down $1.55 to $15.55

The Brazilian company was among battered oil stocks as the price of crude dropped after the International Energy Agency reduced its forecast for demand.


Lakeland Industries Inc., up $2.17 to $23.60

Confirmation of a third case of Ebola in the U.S. and rising fear helped boost shares of the maker of protective and safety gear.

Republic Airways Holdings Inc., down 10 cents to $10.57

Airline stocks were hit after a health worker diagnosed with Ebola flew on a commercial flight, raising concerns the virus scare could curtail travel.

Orexigen Therapeutics Inc., up 52 cents to $3.98

The biotechnology company earned $100 million in milestone payments as the weight-loss drug Contrave is prepared for launch.

Shire PLC, down $75.08 to $170.49

The Ireland-based drug developer's potential buyer, AbbVie, is considering pulling out of the $55 billion deal.