Pfizer's (NYSE:PFE) deal to buy rights to a promising drug from Germany's Merck KGaA will enable it to compete strongly in the fast-growing field of cancer immunotherapy, its research head said.
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Some analysts have criticized Pfizer for being late to the hot new area of cancer research but Mikael Dolsten said on Monday his firm had now put together a strong portfolio of experimental immuno-oncology treatments.
The deal for Merck's MSB0010718C -- part of a class of drugs known as anti-PD-L1 therapies that block a tumor's ability to evade the immune system -- means Pfizer will compete with other "first wave" developers of PD-L1 or related PD-1 drugs, Dolsten said.
"It gives a tremendous acceleration for Pfizer," Dolsten said in a telephone interview. "I would see this partnership making us highly competitive within the first wave of immuno-oncology."
In addition to sharing rights to Merck's drug, for which Pfizer is paying $850 million upfront and up to $2 billion based on future success, Pfizer also has other drugs designed to "check" different parts of the immune system.
"It's part of a long-term commitment to immuno-oncology, so you will see Pfizer introduce every year for quite some time new immuno-onoclogy drugs, either new checkpoint antibodies, vaccines or bi-functional antibodies," Dolsten said.
Citing British takeover rules, he declined to comment on what the tie-up with Merck meant for Pfizer's interest in similar cancer medicine from AstraZeneca
As well as being somewhat later in the development process than rival drugs -- particularly from U.S.-based Merck & Co (NYSE:MRK) and Bristol-Myers Squibb (NYSE:BMY) -- Merck KGaA's has also been linked with lymphopenia, or abnormally low levels of white blood cells called lymphocytes in some patients.
However, Dolsten said he did not believe this was a clinically significant concern. "We don't see that as an issue," he said.
(Editing by Robin Pomeroy)