Health Care

Pharmaceutical and consumer goods maker GlaxoSmithKline says first-quarter revenue dropped 2 percent as a stronger pound offset encouraging sales of a new shingles treatment.

Japanese drugmaker Takeda has reached a tentative agreement to buy Ireland-based Shire Plc for 46 billion pounds ($64 billion) in one of the biggest pharma deals to date.

Asian shares dipped Wednesday, mirroring a sell-off on Wall Street triggered by worries over slowing growth and falling profits.

U.S. stocks are higher Tuesday morning as investors applaud strong first-quarter results from companies including machinery maker Caterpillar, appliance maker Whirlpool and Fifth Third Bancorp.

Stocks that moved substantially or traded heavily Tuesday: Caterpillar Inc., down $9.55 to $144.44

The U.S. Food and Drug Administration has approved the first drug to slow kidney decline in patients with the most common inherited kidney disease.

Audi is recalling about 391,000 cars and SUVs in the U.S. and Canada because the electric coolant pumps can overeat and possibly cause a fire.

Eli Lilly and Co. (LLY) on Tuesday reported first-quarter net income of $1.22 billion, after reporting a loss in the same period a year earlier.

Express Scripts wants to change the pricing model for prescription drugs.

C3 IoT looks to transform fields including agriculture and healthcare.

The U.S. government's highway safety agency is expanding three investigations for brake and air bag troubles that could affect more than 2.3 million vehicles from Ford, Volkswagen and Nissan.

The latest on developments in financial markets (all times local): 9:35 a.m.

Germany's Fresenius and U.S.-based pharmaceutical manufacturer Akorn Inc. are at odds over the German company's decision to terminate a more than $4.3 billion takeover agreement, citing alleged breaches of data integrity requirements.

More than 1 million electrical safety switches are being recalled because of a faulty switch.

Takeda shares fall after Shire rejects $63 billion offer.

When her stay at the glamorous Grancreer residence turned into a nightmare of disrupted sleep and difficulties with the staff, retired harpist Yumi Makino opted out, and after a two-year legal battle got her deposit money back in a rare victory over a big real estate company.

A panel of government health advisers is recommending approval of a medicine made from the marijuana plant to treat childhood epilepsy, moving the medication closer to the U.S. market.

German pharmaceutical and chemical company Merck says it has agreed to sell its global consumer health business to Procter & Gamble for 3.4 billion euros ($4.2 billion) in cash.