| Date | Name | Shares | Transaction | Value |
|
Aug 13, 2026
| Huda Y. Zoghbi Director |
2,503
| Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 Non-derivative transaction at $376.69 per share |
942,855.07
|
|
Aug 13, 2026
| Kathryn W. Guarini Director |
603
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $800 per share |
482,400.00
|
|
Aug 13, 2026
| Huda Y. Zoghbi Director |
N/A
| Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 |
0.00
|
|
Aug 13, 2026
| Kathryn W. Guarini Director |
1,558
| Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 |
0.00
|
|
Aug 13, 2026
| Huda Y. Zoghbi Director |
1,703
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $800 per share |
1,362,400.00
|
|
Aug 13, 2026
| Kathryn W. Guarini Director |
1,003
| Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 Non-derivative transaction at $719.37 per share |
721,528.11
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,786
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $780.69 per share |
13,885,352.34
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,703
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $789.28 per share |
13,972,623.84
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,723
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $788.96 per share |
13,982,738.08
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,743
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $787.34 per share |
13,969,773.62
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,745
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $786.61 per share |
13,958,394.45
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,752
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $785.48 per share |
13,943,840.96
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,763
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $784.48 per share |
13,934,718.24
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,772
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $783.62 per share |
13,926,494.64
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,782
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $782.62 per share |
13,916,548.84
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,784
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $781.21 per share |
13,893,038.64
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,789
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $779.69 per share |
13,869,905.41
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,794
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $778.3 per share |
13,849,070.20
|
|
Mar 4, 2026
| Arthur Frederick Ryan Director |
17,796
| Open market or private sale of non-derivative or derivative security Non-derivative transaction at $777.46 per share |
13,835,678.16
|
|
Dec 12, 2025
| George Damis Yancopoulos Bd. Co-Chair, President & CSO; Director |
442,334
| Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 Non-derivative transaction at $555.67 per share |
245,791,733.78
|