zymeworks inc - ZYME

ZYME

Close Chg Chg %
26.54 -0.21 -0.79%

Closed Market

26.33

-0.21 (0.79%)

Volume: 459.89K

Last Updated:

Dec 31, 2025, 4:00 PM EDT

Company Overview: zymeworks inc - ZYME

ZYME Key Data

Open

$26.53

Day Range

26.15 - 26.88

52 Week Range

9.03 - 28.49

Market Cap

$2.00B

Shares Outstanding

75.41M

Public Float

72.86M

Beta

1.27

Rev. Per Employee

N/A

P/E Ratio

N/A

EPS

-$0.84

Yield

0.00%

Dividend

N/A

EX-DIVIDEND DATE

SHORT INTEREST

N/A

AVERAGE VOLUME

633.22K

 

ZYME Performance

1 Week
 
-2.01%
 
1 Month
 
-1.42%
 
3 Months
 
55.43%
 
1 Year
 
79.85%
 
5 Years
 
-44.29%
 

ZYME Analyst Ratings

  • Sell
  • Under
  • Hold
  • Over
  • Buy
Number of Ratings 14
Full Ratings ➔

About zymeworks inc - ZYME

Zymeworks, Inc. is a biopharmaceutical company, which engages in the discovery, development, and commercialization of novel, multifunctional biotherapeutics. Its product includes Zanidatamab, which is a novel bispecific antibody that targets two distinct domains of the human epidermal growth factor receptor 2 (HER2). Zanidatamab's unique binding properties result in multiple mechanisms of action that may enable it to address unmet need in patient populations with HER2-expressing cancers. The company was founded on September 8, 2003 and is headquartered in Middletown, DE.

ZYME At a Glance

Zymeworks, Inc.
108 Patriot Drive
Middletown, Delaware 19709
Phone 1-302-274-8744 Revenue 76.30M
Industry Pharmaceuticals: Major Net Income -122,695,000.00
Sector Health Technology 2024 Sales Growth 0.384%
Fiscal Year-end 12 / 2025 Employees 286
View SEC Filings

ZYME Valuation

P/E Current N/A
P/E Ratio (with extraordinary items) N/A
P/E Ratio (without extraordinary items) N/A
Price to Sales Ratio 14.552
Price to Book Ratio 3.005
Price to Cash Flow Ratio N/A
Enterprise Value to EBITDA -8.314
Enterprise Value to Sales 11.836
Total Debt to Enterprise Value 0.02

ZYME Efficiency

Revenue/Employee 266,797.203
Income Per Employee -429,003.497
Receivables Turnover 1.367
Total Asset Turnover 0.146

ZYME Liquidity

Current Ratio 3.403
Quick Ratio 3.403
Cash Ratio 2.557

ZYME Profitability

Gross Margin 85.331
Operating Margin -157.034
Pretax Margin -152.824
Net Margin -160.798
Return on Assets -23.505
Return on Equity -30.537
Return on Total Capital -34.342
Return on Invested Capital -29.151

ZYME Capital Structure

Total Debt to Total Equity 5.463
Total Debt to Total Capital 5.18
Total Debt to Total Assets 3.996
Long-Term Debt to Equity 4.654
Long-Term Debt to Total Capital 4.413
  • Income Statement
  • Balance Sheet
  • Cash Flow Statement

Annual Financials for Zymeworks Inc - ZYME

Collapse All in section
All values USD millions. 2021 2022 2023 2024 5-year trend
Sales/Revenue
26.68M 412.48M 76.01M 76.30M
Sales Growth
-31.50% +1,446.03% -81.57% +0.38%
Cost of Goods Sold (COGS) incl D&A
- 12.00M 17.31M 11.19M
COGS excluding D&A
- - - -
-
Depreciation & Amortization Expense
9.58M 12.00M 17.31M 11.19M
Depreciation
6.79M 10.99M 14.60M 6.70M
Amortization of Intangibles
2.79M 1.02M 2.70M 4.50M
COGS Growth
- - +44.16% -35.32%
-
Gross Income
- 400.48M 58.71M 65.11M
Gross Income Growth
- - -85.34% +10.91%
-
Gross Profit Margin
- +97.09% +77.23% +85.33%
2021 2022 2023 2024 5-year trend
SG&A Expense
232.73M 269.95M 196.76M 184.93M
Research & Development
199.75M 208.60M 143.62M 134.62M
Other SG&A
32.98M 61.35M 53.14M 50.31M
SGA Growth
+7.68% +15.99% -27.11% -6.01%
Other Operating Expense
- - - -
-
Unusual Expense
- - - 17.29M
-
EBIT after Unusual Expense
(215.63M) 130.53M (138.05M) (137.11M)
Non Operating Income/Expense
3.27M 4.71M 18.81M 20.50M
Non-Operating Interest Income
1.97M 3.60M 19.71M 19.94M
Equity in Earnings of Affiliates
- - - -
-
Interest Expense
- - - -
-
Interest Expense Growth
- - - -
-
Gross Interest Expense
- - - -
-
Interest Capitalized
- - - -
-
Pretax Income
(212.36M) 135.23M (119.24M) (116.61M)
Pretax Income Growth
-17.90% +163.68% -188.17% +2.21%
Pretax Margin
-795.95% +32.79% -156.87% -152.82%
Income Tax
(516.00K) 10.89M (568.00K) 6.08M
Income Tax - Current - Domestic
437.00K 8.95M 189.00K 5.39M
Income Tax - Current - Foreign
- - - -
-
Income Tax - Deferred - Domestic
(953.00K) 1.94M (757.00K) 691.00K
Income Tax - Deferred - Foreign
- - - -
-
Income Tax Credits
- - - -
-
Equity in Earnings of Affiliates
- - - -
-
Other After Tax Income (Expense)
- - - -
-
Consolidated Net Income
(211.84M) 124.34M (118.67M) (122.70M)
Minority Interest Expense
- - - -
-
Net Income
(211.84M) 124.34M (118.67M) (122.70M)
Net Income Growth
-17.33% +158.69% -195.44% -3.39%
Net Margin Growth
-794.01% +30.14% -156.13% -160.80%
Extraordinaries & Discontinued Operations
- - - -
-
Discontinued Operations
- - - -
-
Net Income After Extraordinaries
(211.84M) 124.34M (118.67M) (122.70M)
Preferred Dividends
- - - -
-
Net Income Available to Common
(211.84M) 124.34M (118.67M) (122.70M)
EPS (Basic)
-4.1092 1.9072 -1.7233 -1.6177
EPS (Basic) Growth
-14.67% +146.41% -190.36% +6.13%
Basic Shares Outstanding
51.55M 65.19M 68.86M 75.85M
EPS (Diluted)
-4.1092 1.9021 -1.7233 -1.6177
EPS (Diluted) Growth
-14.67% +146.29% -190.60% +6.13%
Diluted Shares Outstanding
51.55M 65.25M 68.86M 75.85M
EBITDA
(206.05M) 142.53M (120.75M) (108.63M)
EBITDA Growth
-16.29% +169.17% -184.72% +10.04%
EBITDA Margin
-772.30% +34.55% -158.85% -142.36%

Snapshot

Average Recommendation BUY Average Target Price 35.167
Number of Ratings 14 Current Quarters Estimate -0.095
FY Report Date 03 / 2026 Current Year's Estimate 0.572
Last Quarter’s Earnings -0.44 Median PE on CY Estimate N/A
Year Ago Earnings -0.971 Next Fiscal Year Estimate -0.167
Median PE on Next FY Estimate N/A

Earnings Per Share

This Quarter Next Quarter This Fiscal Next Fiscal
# of Estimates 6 6 13 11
Mean Estimate -0.10 -0.25 0.57 -0.17
High Estimates 0.55 0.24 3.76 2.00
Low Estimate -0.41 -0.77 -1.52 -1.81
Coefficient of Variance -415.16 -139.73 287.78 -647.11

Analysts Recommendations

Current 1 Month Ago 3 Months Ago
BUY 14 11 8
OVERWEIGHT 0 0 0
HOLD 0 1 2
UNDERWEIGHT 0 0 0
SELL 0 0 0
MEAN Buy Buy Buy

Insider Actions for Zymeworks Inc - ZYME

Date Name Shares Transaction Value
Aug 13, 2025 Robert E. Landry Director 62,000 Grant, award or other acq pursuant to Rule 16b-3(d) 0.00
Aug 13, 2025 Gregory A. Ciongoli Director 488,500 Grant, award or other acq pursuant to Rule 16b-3(d) Non-derivative transaction at $12.02 per share 5,871,770.00
Aug 13, 2025 Gregory A. Ciongoli Director 62,000 Grant, award or other acq pursuant to Rule 16b-3(d) 0.00
Apr 8, 2025 EcoR1 Capital, LLC Director 17,503,336 Open market or private purchase of non-derivative security Non-derivative transaction at $11.84 per share 207,239,498.24
Apr 8, 2025 EcoR1 Capital, LLC Director 17,699,774 Open market or private purchase of non-derivative security Non-derivative transaction at $11.17 per share 197,706,475.58
Apr 4, 2025 EcoR1 Capital, LLC Director 17,382,566 Open market or private purchase of non-derivative security Non-derivative transaction at $11.85 per share 205,983,407.10

Zymeworks Inc in the News