lyra therapeutics inc - LYRA

LYRA

Close Chg Chg %
3.41 -0.21 -6.16%

Closed Market

3.20

-0.21 (6.16%)

Volume: 52.31K

Last Updated:

Dec 30, 2025, 4:00 PM EDT

Company Overview: lyra therapeutics inc - LYRA

LYRA Key Data

Open

$3.45

Day Range

3.02 - 3.45

52 Week Range

2.84 - 37.50

Market Cap

$6.05M

Shares Outstanding

1.77M

Public Float

1.63M

Beta

-0.01

Rev. Per Employee

N/A

P/E Ratio

N/A

EPS

-$23.78

Yield

0.00%

Dividend

N/A

EX-DIVIDEND DATE

SHORT INTEREST

N/A

AVERAGE VOLUME

36.21K

 

LYRA Performance

1 Week
 
-10.86%
 
1 Month
 
-13.28%
 
3 Months
 
-54.29%
 
1 Year
 
-68.99%
 
5 Years
 
-99.44%
 

LYRA Analyst Ratings

  • Sell
  • Under
  • Hold
  • Over
  • Buy
Number of Ratings 2
Full Ratings ➔

About lyra therapeutics inc - LYRA

Lyra Therapeutics, Inc. is a clinical-stage therapeutics company. It develops novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose and throat, or ENT, diseases. The firms proprietary XTreo deliver medicines. The company was founded by Carmichael S. Roberts, George M. Whitesides, and Robert S. Langer in November 2005 and is headquartered in Watertown, MA.

LYRA At a Glance

Lyra Therapeutics, Inc.
480 Arsenal Way
Watertown, Massachusetts 02472
Phone 1-617-393-4600 Revenue 1.53M
Industry Pharmaceuticals: Major Net Income -93,435,000.00
Sector Health Technology Employees 30
Fiscal Year-end 12 / 2025
View SEC Filings

LYRA Valuation

P/E Current N/A
P/E Ratio (with extraordinary items) N/A
P/E Ratio (without extraordinary items) N/A
Price to Sales Ratio 8.761
Price to Book Ratio 1.166
Price to Cash Flow Ratio N/A
Enterprise Value to EBITDA -0.12
Enterprise Value to Sales 4.721
Total Debt to Enterprise Value 4.747

LYRA Efficiency

Revenue/Employee 51,133.333
Income Per Employee -3,114,500.00
Receivables Turnover N/A
Total Asset Turnover 0.015

LYRA Liquidity

Current Ratio 3.406
Quick Ratio 3.406
Cash Ratio 3.212

LYRA Profitability

Gross Margin 69.296
Operating Margin -3,959.126
Pretax Margin -6,088.396
Net Margin -6,090.939
Return on Assets -89.435
Return on Equity -184.994
Return on Total Capital -203.234
Return on Invested Capital -122.361

LYRA Capital Structure

Total Debt to Total Equity 296.533
Total Debt to Total Capital 74.781
Total Debt to Total Assets 51.819
Long-Term Debt to Equity 260.988
Long-Term Debt to Total Capital 65.818
  • Income Statement
  • Balance Sheet
  • Cash Flow Statement

Annual Financials for Lyra Therapeutics Inc - LYRA

Collapse All in section
All values USD millions. 2021 2022 2023 2024 5-year trend
Sales/Revenue
285.00K 1.36M 1.56M 1.53M
Sales Growth
- +378.25% +14.31% -1.54%
Cost of Goods Sold (COGS) incl D&A
1.00M 1.07M 278.00K 471.00K
COGS excluding D&A
- - - -
-
Depreciation & Amortization Expense
1.00M 1.07M 278.00K 471.00K
Depreciation
1.00M 1.07M 278.00K 471.00K
Amortization of Intangibles
- - - -
-
COGS Growth
+953.68% +6.59% -73.95% +69.42%
Gross Income
(716.00K) 296.00K 1.28M 1.06M
Gross Income Growth
-653.68% +141.34% +332.43% -16.95%
Gross Profit Margin
-251.23% +21.72% +82.16% +69.30%
2021 2022 2023 2024 5-year trend
SG&A Expense
42.90M 55.29M 66.81M 61.80M
Research & Development
28.69M 37.73M 47.75M 43.30M
Other SG&A
14.21M 17.56M 19.06M 18.50M
SGA Growth
+93.99% +28.87% +20.84% -7.50%
Other Operating Expense
- - - -
-
Unusual Expense
- 1.32M 1.59M 35.62M
EBIT after Unusual Expense
(43.62M) (56.31M) (67.12M) (96.35M)
Non Operating Income/Expense
102.00K 1.04M 4.50M 2.95M
Non-Operating Interest Income
102.00K 1.04M 4.50M 2.95M
Equity in Earnings of Affiliates
- - - -
-
Interest Expense
- - - -
-
Interest Expense Growth
- - - -
-
Gross Interest Expense
- - - -
-
Interest Capitalized
- - - -
-
Pretax Income
(43.51M) (55.27M) (62.62M) (93.40M)
Pretax Income Growth
-96.65% -27.01% -13.31% -49.14%
Pretax Margin
-15,267.72% -4,054.66% -4,019.32% -6,088.40%
Income Tax
- 13.00K 59.00K 39.00K
Income Tax - Current - Domestic
- - - -
-
Income Tax - Current - Foreign
- - - -
-
Income Tax - Deferred - Domestic
- - - -
-
Income Tax - Deferred - Foreign
- - - -
-
Income Tax Credits
- - - -
-
Equity in Earnings of Affiliates
- - - -
-
Other After Tax Income (Expense)
- - - -
-
Consolidated Net Income
(43.51M) (55.28M) (62.68M) (93.44M)
Minority Interest Expense
- - - -
-
Net Income
(43.51M) (55.28M) (62.68M) (93.44M)
Net Income Growth
-96.65% -27.04% -13.39% -49.07%
Net Margin Growth
-15,267.72% -4,055.61% -4,023.11% -6,090.94%
Extraordinaries & Discontinued Operations
- - - -
-
Discontinued Operations
- - - -
-
Net Income After Extraordinaries
(43.51M) (55.28M) (62.68M) (93.44M)
Preferred Dividends
- - - -
-
Net Income Available to Common
(43.51M) (55.28M) (62.68M) (93.44M)
EPS (Basic)
-167.537 -91.412 -62.9265 -71.7475
EPS (Basic) Growth
-29.41% +45.44% +31.16% -14.02%
Basic Shares Outstanding
259.72K 604.71K 996.09K 1.30M
EPS (Diluted)
-167.537 -91.412 -62.9265 -71.7475
EPS (Diluted) Growth
-29.41% +45.44% +31.16% -14.02%
Diluted Shares Outstanding
259.72K 604.71K 996.09K 1.30M
EBITDA
(42.61M) (53.92M) (65.25M) (60.26M)
EBITDA Growth
-92.70% -26.54% -21.01% +7.64%
EBITDA Margin
-14,952.28% -3,956.20% -4,188.06% -3,928.42%

Snapshot

Average Recommendation HOLD Average Target Price 7.00
Number of Ratings 2 Current Quarters Estimate -1.36
FY Report Date 03 / 2026 Current Year's Estimate -3.625
Last Quarter’s Earnings -1.915 Median PE on CY Estimate N/A
Year Ago Earnings -6.38 Next Fiscal Year Estimate -7.066
Median PE on Next FY Estimate N/A

Earnings Per Share

This Quarter Next Quarter This Fiscal Next Fiscal
# of Estimates 1 1 2 1
Mean Estimate -1.36 -1.54 -3.63 -7.07
High Estimates -1.36 -1.54 -0.99 -7.07
Low Estimate -1.36 -1.54 -6.26 -7.07
Coefficient of Variance N/A N/A -102.80 N/A

Analysts Recommendations

Current 1 Month Ago 3 Months Ago
BUY 0 0 0
OVERWEIGHT 0 0 0
HOLD 2 2 4
UNDERWEIGHT 0 0 0
SELL 0 0 0
MEAN Hold Hold Hold

Insider Actions for Lyra Therapeutics Inc - LYRA

Date Name Shares Transaction Value
Nov 17, 2025 Perceptive Advisors LLC 161,318 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $4.31 per share 695,280.58
Nov 17, 2025 Perceptive Advisors LLC 18,122 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $4.31 per share 78,105.82
Nov 17, 2025 Perceptive Advisors LLC 153,456 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $4.06 per share 623,031.36
Nov 17, 2025 Perceptive Advisors LLC 17,239 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $4.06 per share 69,990.34
Nov 17, 2025 Perceptive Advisors LLC 124,859 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $3.9 per share 486,950.10
Nov 17, 2025 Perceptive Advisors LLC 14,026 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $3.9 per share 54,701.40

Lyra Therapeutics Inc in the News