ionis pharmaceuticals inc. - IONS

IONS

Close Chg Chg %
58.25 -1.50 -2.58%

Closed Market

56.75

-1.50 (2.58%)

Volume: 5.10M

Last Updated:

Jul 13, 2026, 4:00 PM EDT

Company Overview: ionis pharmaceuticals inc. - IONS

IONS Key Data

Open

$57.91

Day Range

56.11 - 57.91

52 Week Range

40.03 - 86.74

Market Cap

$9.63B

Shares Outstanding

165.26M

Public Float

162.03M

Beta

0.37

Rev. Per Employee

N/A

P/E Ratio

N/A

EPS

-$2.00

Yield

0.00%

Dividend

N/A

EX-DIVIDEND DATE

SHORT INTEREST

N/A

AVERAGE VOLUME

3.84M

 

IONS Performance

1 Week
 
-28.79%
 
1 Month
 
-20.50%
 
3 Months
 
-22.51%
 
1 Year
 
39.59%
 
5 Years
 
59.37%
 

IONS Analyst Ratings

  • Sell
  • Under
  • Hold
  • Over
  • Buy
Number of Ratings 26
Full Ratings ➔

About ionis pharmaceuticals inc. - IONS

Ionis Pharmaceuticals, Inc. engages in the development and commercialization of human therapeutic drugs using antisense technology. The company was founded by Stanley T. Crooke, David J. Ecker, Christopher K. Mirabelli, and Brett P. Monia on January 10, 1989 and is headquartered in Carlsbad, CA.

IONS At a Glance

Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, California 92010
Phone 1-760-931-9200 Revenue 943.71M
Industry Pharmaceuticals: Major Net Income -381,387,000.00
Sector Health Technology 2025 Sales Growth 33.834%
Fiscal Year-end 12 / 2026 Employees 1,402
View SEC Filings

IONS Valuation

P/E Current N/A
P/E Ratio (with extraordinary items) N/A
P/E Ratio (without extraordinary items) N/A
Price to Sales Ratio 13.413
Price to Book Ratio 26.415
Price to Cash Flow Ratio N/A
Enterprise Value to EBITDA -35.085
Enterprise Value to Sales 13.347
Total Debt to Enterprise Value 0.208

IONS Efficiency

Revenue/Employee 673,117.689
Income Per Employee -272,030.67
Receivables Turnover 14.286
Total Asset Turnover 0.289

IONS Liquidity

Current Ratio 3.826
Quick Ratio 3.814
Cash Ratio 3.426

IONS Profitability

Gross Margin 96.995
Operating Margin -40.445
Pretax Margin -40.224
Net Margin -40.414
Return on Assets -11.686
Return on Equity -70.795
Return on Total Capital -12.289
Return on Invested Capital -14.702

IONS Capital Structure

Total Debt to Total Equity 534.53
Total Debt to Total Capital 84.24
Total Debt to Total Assets 74.19
Long-Term Debt to Equity 441.878
Long-Term Debt to Total Capital 69.639
  • Income Statement
  • Balance Sheet
  • Cash Flow Statement

Annual Financials for Ionis Pharmaceuticals Inc. - IONS

Collapse All in section
All values USD millions. 2022 2023 2024 2025 5-year trend
Sales/Revenue
587.37M 787.65M 705.14M 943.71M
Sales Growth
-27.53% +34.10% -10.48% +33.83%
Cost of Goods Sold (COGS) incl D&A
36.22M 31.63M 33.20M 28.36M
COGS excluding D&A
- - - -
-
Depreciation & Amortization Expense
22.11M 22.50M 21.99M 22.69M
Depreciation
19.69M 19.94M 19.65M 20.25M
Amortization of Intangibles
2.42M 2.56M 2.34M 2.44M
COGS Growth
+19.14% -12.67% +4.98% -14.60%
Gross Income
551.15M 756.02M 671.93M 915.36M
Gross Income Growth
-29.35% +37.17% -11.12% +36.23%
Gross Profit Margin
+93.83% +95.98% +95.29% +97.00%
2022 2023 2024 2025 5-year trend
SG&A Expense
961.34M 1.11B 1.15B 1.30B
Research & Development
833.15M 899.63M 901.53M 913.18M
Other SG&A
128.19M 210.12M 245.48M 383.86M
SGA Growth
+18.65% +15.44% +3.36% +13.08%
Other Operating Expense
- - - -
-
Unusual Expense
7.33M (11.49M) 2.89M (10.22M)
EBIT after Unusual Expense
(417.52M) (342.24M) (477.97M) (371.46M)
Non Operating Income/Expense
167.66M 89.74M 108.35M 82.41M
Non-Operating Interest Income
25.33M 89.04M 107.02M 97.77M
Equity in Earnings of Affiliates
- - - -
-
Interest Expense
8.12M 81.46M 90.45M 90.54M
Interest Expense Growth
-13.12% +902.92% +11.04% +0.10%
Gross Interest Expense
8.12M 81.46M 90.45M 90.54M
Interest Capitalized
- - - -
-
Pretax Income
(257.99M) (333.96M) (460.07M) (379.60M)
Pretax Income Growth
-785.09% -29.45% -37.76% +17.49%
Pretax Margin
-43.92% -42.40% -65.25% -40.22%
Income Tax
11.74M 32.32M (6.17M) 1.79M
Income Tax - Current - Domestic
11.65M 32.17M (6.34M) 1.56M
Income Tax - Current - Foreign
86.00K 147.00K 169.00K 221.00K
Income Tax - Deferred - Domestic
- - - -
-
Income Tax - Deferred - Foreign
- - - -
-
Income Tax Credits
- - - -
-
Equity in Earnings of Affiliates
- - - -
-
Other After Tax Income (Expense)
- - - -
-
Consolidated Net Income
(269.72M) (366.29M) (453.90M) (381.39M)
Minority Interest Expense
- - - -
-
Net Income
(269.72M) (366.29M) (453.90M) (381.39M)
Net Income Growth
-843.18% -35.80% -23.92% +15.97%
Net Margin Growth
-45.92% -46.50% -64.37% -40.41%
Extraordinaries & Discontinued Operations
- - - -
-
Discontinued Operations
- - - -
-
Net Income After Extraordinaries
(269.72M) (366.29M) (453.90M) (381.39M)
Preferred Dividends
- - - -
-
Net Income Available to Common
(269.72M) (366.29M) (453.90M) (381.39M)
EPS (Basic)
-1.9015 -2.558 -3.0358 -2.3835
EPS (Basic) Growth
-837.62% -34.53% -18.68% +21.49%
Basic Shares Outstanding
141.85M 143.19M 149.51M 160.01M
EPS (Diluted)
-1.9015 -2.558 -3.0358 -2.3835
EPS (Diluted) Growth
-837.62% -34.53% -18.68% +21.49%
Diluted Shares Outstanding
141.85M 143.19M 149.51M 160.01M
EBITDA
(388.09M) (331.23M) (453.09M) (358.99M)
EBITDA Growth
-3,552.23% +14.65% -36.79% +20.77%
EBITDA Margin
-66.07% -42.05% -64.26% -38.04%

Snapshot

Average Recommendation BUY Average Target Price 93.667
Number of Ratings 26 Current Quarters Estimate -1.101
FY Report Date 09 / 2026 Current Year's Estimate -3.661
Last Quarter’s Earnings -1.10 Median PE on CY Estimate N/A
Year Ago Earnings -2.38 Next Fiscal Year Estimate -1.746
Median PE on Next FY Estimate N/A

Earnings Per Share

This Quarter Next Quarter This Fiscal Next Fiscal
# of Estimates 17 17 18 18
Mean Estimate -1.10 -0.91 -3.66 -1.75
High Estimates -0.88 -0.71 -3.11 1.65
Low Estimate -1.25 -1.26 -4.04 -3.68
Coefficient of Variance -9.37 -17.06 -6.87 -75.24

Analysts Recommendations

Current 1 Month Ago 3 Months Ago
BUY 19 20 17
OVERWEIGHT 4 3 4
HOLD 3 4 3
UNDERWEIGHT 0 0 0
SELL 0 0 0
MEAN Buy Buy Buy

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