denali therapeutics inc - DNLI

DNLI

Close Chg Chg %
17.08 0.03 0.18%

Open Market

17.11

+0.03 (0.18%)

Volume: 57.08K

Last Updated:

Jan 12, 2026, 9:39 AM EDT

Company Overview: denali therapeutics inc - DNLI

DNLI Key Data

Open

$17.25

Day Range

16.96 - 17.30

52 Week Range

10.57 - 24.35

Market Cap

$2.65B

Shares Outstanding

156.16M

Public Float

138.87M

Beta

1.05

Rev. Per Employee

N/A

P/E Ratio

N/A

EPS

-$2.91

Yield

0.00%

Dividend

N/A

EX-DIVIDEND DATE

SHORT INTEREST

N/A

AVERAGE VOLUME

1.61M

 

DNLI Performance

1 Week
 
4.98%
 
1 Month
 
-5.01%
 
3 Months
 
11.13%
 
1 Year
 
-10.58%
 
5 Years
 
-76.61%
 

DNLI Analyst Ratings

  • Sell
  • Under
  • Hold
  • Over
  • Buy
Number of Ratings 17
Full Ratings ➔

About denali therapeutics inc - DNLI

Denali Therapeutics, Inc. is a biopharmaceutical company, which engages in the development and commercialization of a portfolio of product candidates for neurodegenerative diseases. Its product pipeline includes LRRK2, RIPK1, TREM2, and Tau. The company was founded by Ryan J. Watts, Marc Tessier-Lavigne, and Alexander Schuth on October 14, 2013 and is headquartered in San Francisco, CA.

DNLI At a Glance

Denali Therapeutics, Inc.
161 Oyster Point Boulevard
San Francisco, California 94080
Phone 1-650-866-8547 Revenue 0.00
Industry Biotechnology Net Income -422,773,000.00
Sector Health Technology Employees 422
Fiscal Year-end 12 / 2025
View SEC Filings

DNLI Valuation

P/E Current N/A
P/E Ratio (with extraordinary items) N/A
P/E Ratio (without extraordinary items) N/A
Price to Sales Ratio N/A
Price to Book Ratio 2.364
Price to Cash Flow Ratio N/A
Enterprise Value to EBITDA -5.21
Enterprise Value to Sales N/A
Total Debt to Enterprise Value 0.021

DNLI Efficiency

Revenue/Employee N/A
Income Per Employee -1,001,831.754
Receivables Turnover N/A
Total Asset Turnover N/A

DNLI Liquidity

Current Ratio 8.458
Quick Ratio 8.458
Cash Ratio 8.144

DNLI Profitability

Gross Margin N/A
Operating Margin N/A
Pretax Margin N/A
Net Margin N/A
Return on Assets -33.446
Return on Equity -37.403
Return on Total Capital -32.926
Return on Invested Capital -36.013

DNLI Capital Structure

Total Debt to Total Equity 4.418
Total Debt to Total Capital 4.231
Total Debt to Total Assets 3.953
Long-Term Debt to Equity 3.439
Long-Term Debt to Total Capital 3.293
  • Income Statement
  • Balance Sheet
  • Cash Flow Statement

Annual Financials for Denali Therapeutics Inc - DNLI

Collapse All in section
All values USD millions. 2021 2022 2023 2024 5-year trend
Sales/Revenue
- 48.66M 108.46M 330.53M
Sales Growth
-85.50% +122.90% +204.74% -100.00%
Cost of Goods Sold (COGS) incl D&A
5.61M 7.03M 16.73M 7.79M
COGS excluding D&A
- - - -
-
Depreciation & Amortization Expense
5.61M 7.03M 16.73M 7.79M
Depreciation
5.61M 7.03M 16.73M 7.79M
Amortization of Intangibles
- - - -
-
COGS Growth
- +25.37% +137.86% -53.40%
Gross Income
43.05M 101.43M 313.81M (7.79M)
Gross Income Growth
- +135.60% +209.38% -102.48%
Gross Profit Margin
- +88.47% +93.52% +94.94%
2021 2022 2023 2024 5-year trend
SG&A Expense
338.80M 442.18M 510.50M 494.08M
Research & Development
265.35M 358.73M 423.88M 396.44M
Other SG&A
73.45M 83.44M 86.63M 97.64M
SGA Growth
+27.00% +30.51% +15.45% -3.22%
Other Operating Expense
- - - -
-
Unusual Expense
- - - -
-
EBIT after Unusual Expense
(295.75M) (340.74M) (196.70M) (501.88M)
Non Operating Income/Expense
4.59M 14.77M 51.51M 79.17M
Non-Operating Interest Income
4.59M 14.77M 51.51M 64.64M
Equity in Earnings of Affiliates
- - - -
-
Interest Expense
- - - -
-
Interest Expense Growth
- - - -
-
Gross Interest Expense
- - - -
-
Interest Capitalized
- - - -
-
Pretax Income
(291.16M) (325.97M) (145.19M) (422.70M)
Pretax Income Growth
-504.61% -11.96% +55.46% -191.13%
Pretax Margin
- -598.34% -300.54% -43.93%
Income Tax
(575.00K) 21.00K 30.00K 68.00K
Income Tax - Current - Domestic
- - (576.00K) 7.00K
-
Income Tax - Current - Foreign
1.00K 14.00K 30.00K 68.00K
Income Tax - Deferred - Domestic
- - - -
-
Income Tax - Deferred - Foreign
- - - -
-
Income Tax Credits
- - - -
-
Equity in Earnings of Affiliates
- - - -
-
Other After Tax Income (Expense)
- - - -
-
Consolidated Net Income
(290.58M) (325.99M) (145.22M) (422.77M)
Minority Interest Expense
- - - -
-
Net Income
(290.58M) (325.99M) (145.22M) (422.77M)
Net Income Growth
-508.49% -12.19% +55.45% -191.12%
Net Margin Growth
- -597.15% -300.56% -43.94%
Extraordinaries & Discontinued Operations
- - - -
-
Discontinued Operations
- - - -
-
Net Income After Extraordinaries
(290.58M) (325.99M) (145.22M) (422.77M)
Preferred Dividends
- - - -
-
Net Income Available to Common
(290.58M) (325.99M) (145.22M) (422.77M)
EPS (Basic)
-2.3911 -2.5969 -1.0572 -2.5705
EPS (Basic) Growth
-466.28% -8.61% +59.29% -143.14%
Basic Shares Outstanding
121.52M 125.53M 137.37M 164.47M
EPS (Diluted)
-2.3911 -2.5969 -1.0572 -2.5705
EPS (Diluted) Growth
-478.82% -8.61% +59.29% -143.14%
Diluted Shares Outstanding
121.52M 125.53M 137.37M 164.47M
EBITDA
(290.14M) (333.71M) (179.97M) (494.08M)
EBITDA Growth
-521.17% -15.02% +46.07% -174.53%
EBITDA Margin
- -596.25% -307.67% -54.45%

Snapshot

Average Recommendation BUY Average Target Price 32.286
Number of Ratings 17 Current Quarters Estimate -0.761
FY Report Date 03 / 2026 Current Year's Estimate -2.827
Last Quarter’s Earnings -0.75 Median PE on CY Estimate N/A
Year Ago Earnings -2.986 Next Fiscal Year Estimate -2.565
Median PE on Next FY Estimate N/A

Earnings Per Share

This Quarter Next Quarter This Fiscal Next Fiscal
# of Estimates 10 9 18 15
Mean Estimate -0.76 -0.69 -2.83 -2.56
High Estimates -0.70 0.15 -1.77 -1.43
Low Estimate -0.82 -0.86 -3.69 -3.53
Coefficient of Variance -5.90 -46.07 -20.01 -19.95

Analysts Recommendations

Current 1 Month Ago 3 Months Ago
BUY 16 16 17
OVERWEIGHT 1 1 1
HOLD 0 0 0
UNDERWEIGHT 0 0 0
SELL 0 0 0
MEAN Buy Buy Buy

Denali Therapeutics Inc in the News