apellis pharmaceuticals inc - APLS

APLS

Close Chg Chg %
40.39 0.02 0.05%

Closed Market

40.41

+0.02 (0.05%)

Volume: 10.33M

Last Updated:

Apr 2, 2026, 4:00 PM EDT

Company Overview: apellis pharmaceuticals inc - APLS

APLS Key Data

Open

$40.38

Day Range

40.35 - 40.48

52 Week Range

16.10 - 40.48

Market Cap

$5.17B

Shares Outstanding

127.83M

Public Float

104.43M

Beta

-0.20

Rev. Per Employee

N/A

P/E Ratio

234.40

EPS

$0.17

Yield

0.00%

Dividend

N/A

EX-DIVIDEND DATE

SHORT INTEREST

N/A

AVERAGE VOLUME

7.75M

 

APLS Performance

1 Week
 
138.13%
 
1 Month
 
101.35%
 
3 Months
 
56.26%
 
1 Year
 
102.35%
 
5 Years
 
-6.67%
 

APLS Analyst Ratings

  • Sell
  • Under
  • Hold
  • Over
  • Buy
Number of Ratings 21
Full Ratings ➔

About apellis pharmaceuticals inc - APLS

Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company, which engages in the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. Its products include EMPAVELI and SYFOVRE. The company was founded by Candace Rose Depp, Pascal Deschatelets, Cedric Francois, and Alec Machiels on September 25, 2009 and is headquartered in Waltham, MA.

APLS At a Glance

Apellis Pharmaceuticals, Inc.
100 5th Avenue
Waltham, Massachusetts 02451-8703
Phone 1-617-977-5700 Revenue 1.00B
Industry Pharmaceuticals: Major Net Income 22.39M
Sector Health Technology 2025 Sales Growth 28.465%
Fiscal Year-end 12 / 2026 Employees 739
View SEC Filings

APLS Valuation

P/E Current 234.397
P/E Ratio (with extraordinary items) N/A
P/E Ratio (without extraordinary items) 145.708
Price to Sales Ratio 3.25
Price to Book Ratio 8.593
Price to Cash Flow Ratio 71.97
Enterprise Value to EBITDA 57.358
Enterprise Value to Sales 3.256
Total Debt to Enterprise Value 0.145

APLS Efficiency

Revenue/Employee 1,358,297.70
Income Per Employee 30,294.993
Receivables Turnover 2.741
Total Asset Turnover 1.024

APLS Liquidity

Current Ratio 3.136
Quick Ratio 2.696
Cash Ratio 1.446

APLS Profitability

Gross Margin 89.815
Operating Margin 5.522
Pretax Margin 2.402
Net Margin 2.23
Return on Assets 2.284
Return on Equity 7.479
Return on Total Capital 2.651
Return on Invested Capital 3.12

APLS Capital Structure

Total Debt to Total Equity 128.154
Total Debt to Total Capital 56.17
Total Debt to Total Assets 44.116
Long-Term Debt to Equity 100.936
Long-Term Debt to Total Capital 44.24
  • Income Statement
  • Balance Sheet
  • Cash Flow Statement

Annual Financials for Apellis Pharmaceuticals Inc - APLS

Collapse All in section
All values USD millions. 2022 2023 2024 2025 5-year trend
Sales/Revenue
75.42M 396.59M 781.37M 1.00B
Sales Growth
+13.31% +425.83% +97.02% +28.46%
Cost of Goods Sold (COGS) incl D&A
7.12M 60.21M 117.72M 102.24M
COGS excluding D&A
- - - -
-
Depreciation & Amortization Expense
1.49M 1.70M 1.80M 1.56M
Depreciation
1.49M 1.70M 1.80M 1.56M
Amortization of Intangibles
- - - -
-
COGS Growth
+320.98% +745.35% +95.51% -13.16%
Gross Income
68.30M 336.38M 663.64M 901.55M
Gross Income Growth
+5.28% +392.51% +97.29% +35.85%
Gross Profit Margin
+90.56% +84.82% +84.93% +89.81%
2022 2023 2024 2025 5-year trend
SG&A Expense
662.91M 853.50M 828.62M 846.12M
Research & Development
387.24M 354.39M 327.57M 295.85M
Other SG&A
275.68M 499.11M 501.05M 550.26M
SGA Growth
+10.27% +28.75% -2.91% +2.11%
Other Operating Expense
- - - -
-
Unusual Expense
- - 32.89M 1.95M
-
EBIT after Unusual Expense
(627.50M) (517.12M) (166.93M) 55.43M
Non Operating Income/Expense
8.63M 20.21M 10.60M 13.01M
Non-Operating Interest Income
8.91M 20.93M 12.77M 13.14M
Equity in Earnings of Affiliates
- - - -
-
Interest Expense
32.63M 29.58M 40.39M 44.33M
Interest Expense Growth
+146.40% -9.33% +36.54% +9.74%
Gross Interest Expense
32.63M 29.58M 40.39M 44.33M
Interest Capitalized
- - - -
-
Pretax Income
(651.50M) (526.50M) (196.72M) 24.11M
Pretax Income Growth
+12.67% +19.19% +62.64% +112.26%
Pretax Margin
-863.81% -132.76% -25.18% +2.40%
Income Tax
669.00K 2.13M 1.16M 1.72M
Income Tax - Current - Domestic
520.00K 1.87M 474.00K 1.55M
Income Tax - Current - Foreign
149.00K 263.00K 688.00K 172.00K
Income Tax - Deferred - Domestic
- - - -
-
Income Tax - Deferred - Foreign
- - - -
-
Income Tax Credits
- - - -
-
Equity in Earnings of Affiliates
- - - -
-
Other After Tax Income (Expense)
- - - -
-
Consolidated Net Income
(652.17M) (528.63M) (197.88M) 22.39M
Minority Interest Expense
- - - -
-
Net Income
(652.17M) (528.63M) (197.88M) 22.39M
Net Income Growth
+12.62% +18.94% +62.57% +111.31%
Net Margin Growth
-864.70% -133.29% -25.32% +2.23%
Extraordinaries & Discontinued Operations
- - - -
-
Discontinued Operations
- - - -
-
Net Income After Extraordinaries
(652.17M) (528.63M) (197.88M) 22.39M
Preferred Dividends
- - - -
-
Net Income Available to Common
(652.17M) (528.63M) (197.88M) 22.39M
EPS (Basic)
-6.146 -4.4543 -1.597 0.1775
EPS (Basic) Growth
+30.48% +27.53% +64.15% +111.11%
Basic Shares Outstanding
106.11M 118.68M 123.91M 126.14M
EPS (Diluted)
-6.146 -4.4543 -1.597 0.1724
EPS (Diluted) Growth
+30.48% +27.53% +64.15% +110.80%
Diluted Shares Outstanding
106.11M 118.68M 123.91M 129.85M
EBITDA
(593.13M) (515.42M) (163.18M) 56.98M
EBITDA Growth
-10.91% +13.10% +68.34% +134.92%
EBITDA Margin
-786.41% -129.96% -20.88% +5.68%

Snapshot

Average Recommendation HOLD Average Target Price 38.765
Number of Ratings 21 Current Quarters Estimate -0.32
FY Report Date 06 / 2026 Current Year's Estimate -1.116
Last Quarter’s Earnings -0.30 Median PE on CY Estimate N/A
Year Ago Earnings 0.20 Next Fiscal Year Estimate -0.126
Median PE on Next FY Estimate N/A

Earnings Per Share

This Quarter Next Quarter This Fiscal Next Fiscal
# of Estimates 21 21 21 21
Mean Estimate -0.32 -0.26 -1.12 -0.13
High Estimates -0.16 -0.10 -0.38 1.51
Low Estimate -0.49 -0.60 -2.19 -2.02
Coefficient of Variance -24.70 -36.09 -30.85 -589.07

Analysts Recommendations

Current 1 Month Ago 3 Months Ago
BUY 2 3 12
OVERWEIGHT 0 0 2
HOLD 19 18 7
UNDERWEIGHT 0 0 0
SELL 0 0 1
MEAN Hold Hold Overweight

Insider Actions for Apellis Pharmaceuticals Inc - APLS

Date Name Shares Transaction Value
Mar 4, 2026 Mikael Dolsten Director 14,312 Grant, award or other acq pursuant to Rule 16b-3(d) 0.00
Mar 4, 2026 Mikael Dolsten Director 24,135 Grant, award or other acq pursuant to Rule 16b-3(d) 0.00
Jan 16, 2026 Pascal Deschatelets Chief Scientific Officer 1,158,219 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $22.19 per share 25,700,879.61
Jan 16, 2026 Nur Nicholson Chief Technical Officer 81,046 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $22.19 per share 1,798,410.74
Jan 16, 2026 Mark DeLong Chief Business & Strat Officer 83,058 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $22.19 per share 1,843,057.02
Jan 16, 2026 David O. Watson General Counsel 98,838 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $22.19 per share 2,193,215.22
Jan 16, 2026 James G. Chopas VP/Chief Accounting Officer 52,595 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $22.19 per share 1,167,083.05
Jan 16, 2026 Timothy Eugene Sullivan Chief Financial Officer 107,080 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $22.19 per share 2,376,105.20
Jan 16, 2026 Cedric Francois Chief Executive Officer; Director 321,419 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $22.19 per share 7,132,287.61
Sep 11, 2025 Timothy Eugene Sullivan Chief Financial Officer 60,396 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $27.83 per share 1,680,820.68
Sep 11, 2025 Timothy Eugene Sullivan Chief Financial Officer 242,903 Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00
Sep 11, 2025 Timothy Eugene Sullivan Chief Financial Officer 110,936 Open market or private sale of non-derivative or derivative security Non-derivative transaction at $27.86 per share 3,090,676.96
Sep 4, 2025 Kelley Boucher Chief People Officer 97,658 Grant, award or other acq pursuant to Rule 16b-3(d) 0.00
Sep 4, 2025 Kelley Boucher Chief People Officer 45,766 Grant, award or other acq pursuant to Rule 16b-3(d) 0.00
Sep 3, 2025 Leslie Meltzer Chief Research and Development 61,804 Grant, award or other acq pursuant to Rule 16b-3(d) 0.00
Sep 3, 2025 Leslie Meltzer Chief Research and Development 92,592 Grant, award or other acq pursuant to Rule 16b-3(d) 0.00
Jun 12, 2025 Caroline Baumal Chief Medical Officer 82,500 Grant, award or other acq pursuant to Rule 16b-3(d) 0.00
May 23, 2025 Pascal Deschatelets Chief Scientific Officer N/A Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 0.00

Apellis Pharmaceuticals Inc in the News