Why bluebird bio Shares Rallied 24.7% In November

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What happened

After business-friendly Donald Trump's presidential victory, and ahead of phase 1 interim trial results for its multiple myeloma therapy on Nov. 30, shares in bluebird bio (NASDAQ: BLUE) soared 24.7% last month,according toS&P Global Market Intelligence.

So what

Fear that drug pricing would fall into the regulatory crosshairs if Hillary Clinton won the White House decreased afterDonald Trump was elected on Nov 8. Trump ran on a deregulation, free-market platform that suggests biotech companies have less to worry about now that he'll be the next president.

Trump's industry-friendly status sent Bluebird's shares soaring from $46.10 on election night to $63.60 on Nov. 15. Shares continued to climb into the end of November after management told investors on Nov. 14 that they would present interim results from Bluebird's multiple myeloma phase 1 trial at a symposium on Dec. 1.

BLUE data by YCharts.

Now what

Management reported interim data ahead of the symosium on Nov. 30, and it didn't disappoint. So far, Bluebird's bb2121, which is being developed in collaboration withmultiple myeloma powerhouse Celgene(NASDAQ: CELG), is delivering bothhigh response rates and top-notch safety.

In the nine-person trial, bb2121's response rate was78%, including two complete responses that were maintained at the four- and six-month mark, respectively. Furthermore, no dose-limiting toxicities, grade 3 or grade 4 cases of cytokine release syndrome, nor any grade 3 or grade 4 neurotoxicity have been observed yet.

The results are intriguing because the average person participating in this study received a median six prior treatments before receiving bb2121. Assuming that bb2121 continues to produce high response rates and solid safety in tough-to-treat patients like these, it could someday reshape multiple myeloma treatment. Of course, it doesn't hurt to have Celgene's significant experience in the indication at its disposal, either. Celgene already markets the best-selling first-, second-, and third-line multiple myeloma drugs on the market.

Nevertheless, there's no guarantee that bb2121's future studies will pan out, and given that more than 90% of cancer drug trials fail, some caution may be warranted now that Bluebird's shares have catapulted its market cap to $2.6 billion.

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Todd Campbell owns shares of Celgene.Todd owns E.B. Capital Markets, LLC. E.B. Capital's clients may have positions in the companies mentioned.Like this article? Follow him onTwitter where he goes by the handle@ebcapitalto see more articles like this.

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