Target, Lowe's, Staples, Dish Network and Cliffs Natural Resources are big market movers

Stocks that moved substantially or traded heavily Wednesday on the New York Stock Exchange and the Nasdaq Stock Market:

NYSE

Target Corp., up $4.99 to $72.50

The retailer reported a boost in third-quarter profit, marking a rebound from a massive data breach and topping expectations.

Lowe's Cos., up $3.73 to $62.26

The home improvement retailer's third-quarter profit jumped on a recovery in the housing market, beating Wall Street expectations.

Cliffs Natural Resources Inc., down $2.04 to $8.17

The mining company is pursuing options for exiting its Eastern Canadian iron ore operations, including closing its Bloom Lake mine.

Vipshop Holdings Ltd., down $1.27 to $22.44

The Chinese online discount retailer reported better-than-expected third-quarter results and issued positive guidance.

Nasdaq

Staples Inc., up $1.16 to $13.92

The office supplies retailer met Wall Street's profit expectations on better-than-expected quarterly revenue results.

Oplink Communications Inc., up $2.93 to $24.18

The optical networking equipment company said it will be acquired by Koch Industries in an all-cash deal worth $445 million.

Dish Network Corp., up $6.81 to $74.66

The increase in price of a government radio spectrum auction helped boost the television service provider's stock.

Agios Pharmaceuticals Inc., up $12.16 to $95.97

The biopharmaceutical company reported promising results from an early stage study of a potential advanced leukemia treatment.