Stocks that moved substantially or traded heavily Wednesday on the New York Stock Exchange and the Nasdaq Stock Market:
Puma Biotechnology Inc. (PBYI), down $27.33 to $197.67
The biotechnology company said it will delay filing for marketing approval until 2016 for an experimental breast cancer drug.
Abercrombie & Fitch Co. (ANF), up 97 cents to $28.81
The clothing and apparel retailer reported better-than-expected quarterly profit, but its revenue fell short of forecasts.
Cliffs Natural Resources Inc. (CLF), up 44 cents to $8.60
The mining company is selling off coal assets in West Virginia as it continues to shift more toward being an iron ore supplier.
Transocean Ltd. (RIG), up 19 cents to $19.57
The offshore drilling services company and its peers saw shares rise as oil prices rose slightly following a period of decline.
Carbonite Inc. (CARB), up $2.68 to $14.44
The cloud-based data backup company confirmed that it received and will review a buyout offer from J2 Global for $15 per share.
Sequenom Inc. (SQNM), up 72 cents to $3.77
The life sciences and diagnostics company has settled all patent infringement claims and disputes with Verinata Health Inc.
Idera Pharmaceuticals Inc. (IDRA), up 49 cents to $4.07
The biotechnology company reported promising test results from a preclinical study focusing on a potential cancer treatment.
Tesla Motors Inc. (TSLA), down $2.13 to $229.30
The electric car maker saw shares continue to fall as gasoline prices slide and traditional auto sales jumped in November.