Novo Nordisk, Transocean, Walgreen, Adamas and Novo Nordisk are big market movers

Stocks that moved substantially or traded heavily Wednesday on the New York Stock Exchange and the Nasdaq Stock Market:

NYSE

Novo Nordisk AS, up 95 cents to $43.67

U.S. regulators approved the pharmaceutical company's diabetes drug to be used to treat obesity, the first injectable cleared for weight loss.

Walgreen Co., up 16 cents to $76.67

Wall Street is ecstatic over the numbers from the drug store's latest quarter, with many analysts upping their price targets on the stock.

Brookfield Residential Properties Inc., up $1.15 to $24.01

Brookfield Asset Management is buying the slice of the land developer it does not own after upping its offer by more than 5 percent.

Transocean Ltd., down 37 cents to $18.77

Crude prices that stabilized this week after months of declines slumped again and dragged big energy companies down with them.

Nasdaq

Taser International Inc., 85 cents to $26.87

Major orders continue to roll in for the maker of defense equipment used by police departments, particularly its body cameras.

GoPro Inc., up $4.87 to $66.41

Wall Street has been down on the adventure camera maker but Wedbush says consumers love it and major retailers are selling out.

Virgin America Inc., up $5.19 to $41

Analysts have tried to single out which airlines will win big with oil prices dropping, and Virgin is the latest favorite.

Adamas Pharmaceuticals Inc., $1.45 to $16.10

A new application for Namzaric from the drugmaker and partner Actavis was approved by the FDA for Alzheimer's-type dementia.