The latest on developments in financial markets (All times local):
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Major U.S. stock indexes nudged a bit further into record territory on Wall Street, but small-company stocks lagged behind.
Gains for health care and retail companies were partly offset by declines in major technology stocks Wednesday.
Amazon rose 1 percent, and drugmaker Mylan soared 16 percent after federal regulators approved its generic version of Teva's multiple sclerosis drug Copaxone.
Facebook fell 1 percent.
The Standard & Poor's 500 edged up 3 points, or 0.1 percent, to 2,537.
The Dow Jones industrial average gained 19 points, or 0.1 percent, to 22,661, and the Nasdaq edged up 2 points, less than 0.1 percent, to 6,534.
The Russell 2000 index of smaller companies fell 4 points, or 0.3 percent, to 1,507.
More stocks fell than rose on the New York Stock Exchange.
Stocks are slightly higher in midday trading on Wall Street, pushing indexes further into record territory.
If the Standard & Poor's 500 index closes higher on Wednesday, it will mark the 7th gain in a row.
Consumer-focused companies and health care stocks were rising more than the rest of the market.
Amazon rose 1 percent, and drugmaker Mylan soared 18 percent after federal regulators approved its generic version of Teva's multiple sclerosis drug Copaxone.
The Standard & Poor's 500 index was up 4 points, or 0.2 percent, to 2,539.
The Dow Jones industrial average gained 38 points, or 0.2 percent, to 22,680, and the Nasdaq composite edged up 7 points, or 0.1 percent, to 6,538.
Stocks are off to a mixed start on Wall Street as gains for retailers and health care companies are offset by losses elsewhere in the market.
Pepsi is off 2 percent early Wednesday after it reported weaker-than-expected sales and lowered its revenue forecast.
Office Depot is down 15 percent after it said it will buy CompuCom for $1 billion. The company also cut its forecast for operating income.
Spain's main stock index is down 2 percent on reports the government in Catalonia will declare independence.
The Standard & Poor's 500 index was down a fraction of a point at 2,533.
The Dow Jones industrial average gained 8 points, less than 0.1 percent, to 22,650, and the Nasdaq composite fell 4 points, or 0.1 percent, to 6,527.