Stocks that moved substantially or traded heavily Wednesday:
Juno Therapeutics Inc., up $23.65 to $69.25
The Wall Street Journal reported that biotech drugmaker Celgene may buy the cancer therapy company.
Ford Motor Co., down 92 cents to $12.18
The automaker gave a disappointing profit forecast that included weaker sales and higher commodity costs and investment expenses.
Boeing Co., up $15.85 to $351.01
The Federal Reserve said U.S. industrial production rallied 0.9 percent in December.
Goldman Sachs Group Inc., down $4.81 to $253.65
The investment bank posted its first quarterly loss in more than six years and also said its trading desks had a weak quarter.
Dentsply Sirona Inc., down $3 to $62.65
The dental supply company named Donald Casey Jr. as its new CEO.
Ethan Allen Interiors Inc., down $2.05 to $26.10
The home furnishings company said problems including a decline in customer visits and delayed shipments hurt it in the second quarter.
General Electric Co., down 86 cents to $17.35
The industrial conglomerate's stock continued to fall after the company said it needs to pay billions to shore up its finance arm.
Bank of America Corp., down 6 cents to $31.18
The consumer bank's fourth-quarter profit fell because of changes in tax law and a decline in trading revenue.