Instant Analysis: Biogen's Anti-Lingo-1 Flunks Game-Changing Study In MS

Image source: Biogen Inc.

What happened

Biogen Inc. reported today that its next-generation drug, anti-lingo-1, oropicinumab, failed to reverse the effects of multiple sclerosis.

Why it matters

Opicinumab was being studied as a next-generation multiple sclerosis medicine that could reverse the disease by repairing damage to myelin, a protective sheath that encapsulates nerve fibers and increases the speed at which nerve signals are communicated.

Currently, medicines used to treat multiple sclerosis can slow the progression of the disease, but they can't reverse it. If opicinumab's study had succeeded, it could have transformed disease treatment, becoming a multi-billion dollar blockbuster drug in the process.

Unfortunately, opicinumab failedto significantly improve physical function, cognitive function, and disability -- the primary endpoints of this mid stage trial. Opicinumab also failed to slowthe progression of disability associated with multiple sclerosis, the trial's secondary endpoint.

The results cast doubt onopicinumab's future, but management is still crunching the data to see how best to refine a future trial that could be more likely to succeed.

What's next

An opicinumab success could have significantly boosted the company's future prospects for sales and profit, but just because opicinumab's future is unclear doesn't necessarily mean that long-term investors should hit the sell button.

Biogen remains the dominant player in the multiple sclerosis treatment market, a market that's valued at $17 billion annually. And, the company's insulated its market share by recently launching longer-lasting multiple sclerosis treatments that reduce patient burden. As a result, Biogen's sales and profit are still climbing. For example, revenue grew 7% to $2.7 billion, and EPS improved 25% to $4.79 in the first quarter.

BIIB Revenue (Quarterly) data by YCharts

Since Biogen's sales and profit are growing and it remains a giant in multiple sclerosis treatment, I think long-minded investors might be better off thinking of today's disappointing news as an opportunity to buy a top-tier biotech on sale. After all, today'sdrop means that investors can pay less than 13 times next year's EPS estimates to buy shares, and that could be a bargain.

The article Instant Analysis: Biogen's Anti-Lingo-1 Flunks Game-Changing Study In MS originally appeared on

Todd Campbell has no position in any stocks mentioned.Todd owns E.B. Capital Markets, LLC. E.B. Capital's clients may have positions in the companies mentioned. Like this article? Follow him onTwitter where he goes by the handle@ebcapital to see more articles like this.The Motley Fool recommends Biogen. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.

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