International stocks trading in New York closed mostly lower on Wednesday.
Deutsche Bank AG (DB) and Barclays PLC (BCS) were among the companies with ADRs that traded actively.
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The BNY Mellon index of American depositary receipts fell 0.2% to 148.4. The European index decreased 0.1% to 138.09, the Asian index dropped 0.4% to 174.62, and the emerging markets fell 0.2% to 314.03.
The Latin American index was the only indicator to see gains rising 0.2% to 238.94.
ADRs of Barclays fell 0.7% to $10.14 after The Wall Street Journal reported the bank would lend $20 billion to back CVS Health Corp.'s takeover of Aetna Inc.
ADRs of Deutsche Bank dropped by 1.4% to $18.50 as the company continued to cope with news it received a subpoena from U.S. Special Counsel Robert Mueller's office concerning people or entities affiliated with President Donald Trump.
ADRs of Alibaba Group Holding (BABA) rose 2.2% to $172.63 after Susquehanna initiated coverage with a positive rating.
ADRs of GlaxoSmithKline PLC (GSK) fell 0.6% to $34.66 despite reporting positive results from a late stage clinical trial of its Shingrix drug.
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(END) Dow Jones Newswires
December 06, 2017 17:35 ET (22:35 GMT)