Health Care

Regeneron and Sanofi announce rebate deal with benefit manager Express Scripts.

The latest on developments in financial markets (all times local): Stocks are opening moderately lower on Wall Street after several companies reported disappointing results.

Merck is reporting strong profits for the first quarter, but revenue is just shy of what many had expected.

Pfizer is reporting strong first-quarter profits, but revenue is short of Wall Street expectations.

The drug, Praluent, dramatically lowers bad LDL cholesterol and reduces the risk of heart attacks and death in high-risk heart patients.

Net income fell to $736 million, or 27 cents per share, in the first quarter from $1.55 billion, or 56 cents per share, a year earlier.

The largest U.S. drugmaker said on Tuesday net profit rose to $3.56 billion or 59 cents per share in the first quarter of 2018, from $3.12 billion or 51 cents per share a year earlier.

More than 100,000 ceiling fans are being recalled because of faulty brackets connecting the fan blades.

Chipotle, which has been working to revive its business after past food safety scares, says a key sales figure rose as it increased prices in most of its restaurants.

The implant was an “absolute game changer,” he says.

CMS administrator Seema Verma said the regulation is part of the effort to make sure patients are put first in health care.

Pharmaceutical and consumer goods maker GlaxoSmithKline says first-quarter revenue dropped 2 percent as a stronger pound offset encouraging sales of a new shingles treatment.

Japanese drugmaker Takeda has reached a tentative agreement to buy Ireland-based Shire Plc for 46 billion pounds ($64 billion) in one of the biggest pharma deals to date.

Asian shares dipped Wednesday, mirroring a sell-off on Wall Street triggered by worries over slowing growth and falling profits.

U.S. stocks are higher Tuesday morning as investors applaud strong first-quarter results from companies including machinery maker Caterpillar, appliance maker Whirlpool and Fifth Third Bancorp.

Stocks that moved substantially or traded heavily Tuesday: Caterpillar Inc., down $9.55 to $144.44

The U.S. Food and Drug Administration has approved the first drug to slow kidney decline in patients with the most common inherited kidney disease.

Audi is recalling about 391,000 cars and SUVs in the U.S. and Canada because the electric coolant pumps can overeat and possibly cause a fire.