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Wednesday, April 7, 2010 as of 11:14 AM ET

Schering-Plough

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Schering-Plough Corporation was a United States-based pharmaceutical company. It was founded in 1851 by Ernst Christian Friedrich Schering as Schering AG in Germany.

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Merck's Anticlotting Drug Effective In Certain Patients

The addition of Merck & Co.

's (MRK) experimental anticlotting drug vorapaxar to standard care reduced the risk of heart attacks and related events by 13% in a study of heart-disease patients, but at a cost of a 66% increase in the risk of significant bleeding versus standard treatment alone.Merck and researchers who led the trial said the data suggest the drug has a significant benefit for heart-attack patients in whom the bleeding risk is modest. That compares with earlier findings that patients with a history of stroke had a substantial risk of serious bleeding.Merck said it would analyze the data with trial investigators and other experts to identify a group of patients who stand to get the most benefit from the drug. Then its challenge would be to persuade the U.S. Food and Drug Administration to approve the drug for such a population despite the overall bleeding risk.John Strony, section head for thrombosis at Merck Research Laboratories, said the company would seek input on the d...

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