Retail sales below analysts’ estimates took a toll on the major indices Wednesday. The Dow fell 2.2%, S&P lost 2.7%, and NASDAQ closed down 3%.

Here are today’s winners and losers:

Winners:

CME Group Inc. (CME)

CME gained 6% as the market ran to commodities Wednesday. It closed the session up $15.62 to $274.10.

General Motors Corp. (GM)

GM set a new 52 week low as it hit $1.00 during trading. The stock finished up 5.2% as it added 6 cents to close at $1.21.

Dr. Pepper Snapple Group Inc. (DPS)

Dr. Pepper beat the street’s estimates as it closed up 3.8%. DPS ended the session up 81 cents to $22.07.

Time Warner Inc. (TWX)

Despite a downgrade by FBR Capital markets, the media company pushed into the positive by 3.4% to close the trading day. TWX closed the day up 80 cents to $24.42.

Merck & Co. Inc. (MRK)

News that the company is attempting to assure capital as it continues to work a deal to purchase Schering-Plough helped the stock gain 2.8%. MRK finished Wednesday up 69 cents to $25.67.

Losers:

Genworth Financial Inc. (GNW)

Genworth continued its slide, announcing first-quarter results.  Shares lost 20.8%. GNW traded down $1.09 to $4.15.

Office Depot Inc. (ODP)

A double whammy for the retailer: a moody’s downgrade along with lower retail sales pushed shares of ODP down 15%. It closed with a 54-cent loss at $3.06.

Huntington Bancshares Inc. (HBAN)

A combination of sector trends and the continued losses since its earnings report cost HBAN 14.9%. It ended the session down 77 cents to $4.41.

Marshall & Ilsley Corp. (MI)

Shares dropped 14.7%, following sector trends. The regional bank closed with a $1.39 loss to $8.06.

Fifth Third Bancorp. (FITB)

Another regional that has dropped since announcing it will sell shares to raise capital is Fifth Third.  FITB fell 14.7%, or $1.21, to close Wednesday at $7.02.