ALISO VIEJO, Calif., May 07, 2008 (BUSINESS WIRE) ----Valeant Pharmaceuticals International (NYSE:VRX) today announced first quarter financial results for 2008.

Revenues:

Total revenue decreased 5% to $194.7 million in the first quarter of 2008 as compared to $204.4 million in the first quarter of 2007.

Product sales increased 8% in the first quarter of 2008 to $181.9 million as compared to $167.9 million reported in the same period last year.

North America product sales increased 15% to $72.3 million in first quarter of 2008, as compared to $62.6 million in the first quarter of 2007, primarily due to increased sales of Efudex and Cesamet.

Sales in the International region declined 17% in the 2008 first quarter to $29.2 million as compared to $35.3 million in the same period last year, due to continuing challenges in our Mexican operations and the divestiture of certain subsidiaries and business operations in Asia.

Sales in the Europe, Middle East and Africa (EMEA) region increased 15% to $80.5 million in the 2008 first quarter as compared to $70.1 million in the same period last year, primarily due to favorable currency fluctuations.

Alliance revenue decreased 65% to $12.8 million in the 2008 first quarter as compared to $36.5 million in the same period last year. Included in the alliance revenue in the first quarter of 2007 was a $19.2 million pradefovir licensing payment from Schering-Plough. Ribavirin royalty decreased 26%, reflecting competitive dynamics in the ribavirin market in Europe and Japan and the cessation of ribavirin royalties from Roche as a result of a loss of patent coverage in Europe.

Continuing Operations:

The company's gross margin on product sales was 70% in the 2008 first quarter as compared to 72% reported in the 2007 first quarter. This decrease primarily reflects the impact of increased inventory reserves.

Selling expense was 35% of product sales in both the 2008 and 2007 first quarter. General and administrative expenses were 14% of product sales in the 2008 first quarter, as compared to 16% in the same period in 2007. In the first quarter of 2007, general and administrative expenses included two unusual items with a net expense of $1.6 million.

Research and development costs were $29.4 million in the 2008 first quarter, compared to $21.0 million in the same period in 2007, an increase of 40%. This increase was due to the retigabine clinical development program.

Net loss from continuing operations was $0.6 million for the first quarter of 2008, or a loss of $0.01 per diluted share as compared to net income from continuing operations of $13.5 million, or $0.14 per diluted share for the first quarter of 2007. Adjusted for non-GAAP items, net loss from continuing operations was $3.9 million or a loss of $0.04 per diluted share as compared to net income of $20.6 million, or $0.21 per diluted share in the first quarter of 2007.

"The financial results from this quarter continue to highlight the need for decisive change at Valeant," said J. Michael Pearson, chairman and chief executive officer. "We have initiated steps to address our cost base and return this company to growth and sustained profitability. While we have many challenges still ahead of us, I am pleased we are now in the execution phase of the turnaround."

Discontinued Operations:

Valeant announced an agreement to sell Infergen on December 20, 2007. The financial results for Infergen are reflected as discontinued operations and prior periods were restated accordingly. Valeant closed the sale in January 2008 for which we received $70.8 million as an upfront payment and expect to receive two payments up to $20.5 million in the next twelve and eighteen months.

Divestitures:

Valeant signed a definitive agreement to sell certain subsidiaries and product rights in certain Asian markets including Singapore, the Philippines, Taiwan, Korea, and China in December 2007. The transaction closed in March 2008 for $37.9 million.

Conference Call and Webcast Information:

Valeant will host a conference call today at 10:00 a.m. EDT (7:00 a.m. PDT) to discuss its 2008 first quarter results. The dial-in number to participate on this call is (877) 295-5743, confirmation code 44566346. International callers should dial (706) 679-0845, confirmation code 44566346. A replay will be available approximately two hours following the conclusion of the conference call through May 14, 2008 and can be accessed by dialing (800) 642-1687, or (706) 645-9291, confirmation code 44566346. The company will also webcast the conference call live over the Internet. The webcast may be accessed through the investor relations section of Valeant's corporate Web site at www.valeant.com.

About Valeant:

Valeant Pharmaceuticals International (NYSE:VRX) is a multinational specialty pharmaceutical company that develops and markets a broad range of pharmaceutical products primarily in the areas of neurology and dermatology. More information about Valeant can be found at www.valeant.com.

Efudex, Cesamet, Diastat AcuDial, Kinerase, Mestinon, Zelapar, Migranal, Bedoyecta, Dermatix and Bisocard are trademarks or registered trademarks of Valeant Pharmaceuticals International or its related companies. All other trademarks are the trademarks or the registered trademarks of their respective owners.

FORWARD-LOOKING STATEMENTS:

This press release contains forward-looking statements, including, but not limited to, statements regarding the need for change, steps to control costs and return the company to growth and profitability and future challenges. These statements are based upon the current expectations and beliefs of management and are subject to certain risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. These risks and uncertainties include, but are not limited to, risks and uncertainties related to the company's ability to realize the expected benefits from its restructuring plans, and other risks and uncertainties discussed in the company's filings with the SEC. Valeant wishes to caution the reader that these factors are among the factors that could cause actual results to differ materially from the expectations described in the forward-looking statements. Valeant also cautions the reader that undue reliance should not be placed on any of the forward-looking statements, which speak only as of the date of this release. The company undertakes no obligation to update any of these forward-looking statements to reflect events or circumstances after the date of this release or to reflect actual outcomes.

NON-GAAP INFORMATION:

To supplement the consolidated financial results prepared in accordance with generally accepted accounting principles (GAAP), the company uses non-GAAP financial measures that exclude certain items, such as special charges and credits. Management does not consider the excluded items part of day-to-day business or reflective of the core operational activities of the company as they result from transactions outside the ordinary course of business. Management uses non-GAAP financial measures internally for strategic decision making, forecasting future results and evaluating current performance. By disclosing non-GAAP financial measures, management intends to provide investors with a more meaningful, consistent comparison of the company's core operating results and trends for the periods presented. Non-GAAP financial measures are not prepared in accordance with GAAP; therefore, the information is not necessarily comparable to other companies and should be considered as a supplement to, not a substitute for, or superior to, the corresponding measures calculated in accordance with GAAP.

Financial Tables, including a reconciliation of GAAP to non-GAAP financial measures, follow.

 Valeant Pharmaceuticals International Table 1 Consolidated Condensed Statement of Income For the Three Months
   Ended March 31, 2008 and 2007 Three Months Ended March 31, ------------------- (In thousands, except per share data) 2008
   2007 % Change --------- --------- -------- Product sales $181,913 $167,933 8% Alliance revenue (including ribavirin royalties)
   (a) 12,773 36,470 -65% --------- --------- Total revenues 194,686 204,403 -5% --------- --------- Cost of goods sold 54,890
   46,901 17% Selling expenses 63,790 58,440 9% General and administrative expenses 26,106 26,115 0% Research and development
   costs 29,392 20,990 40% Restructuring, asset impairments and dispositions (12,664) 7,238 NM Amortization expense 18,066 17,481
   3% --------- --------- 179,580 177,165 1% --------- --------- Income from operations 15,106 27,238 Interest expense, net (4,773)
   (6,441) Other income (expense), net including translation and exchange (3,252) 1,136 --------- --------- Income from continuing
   operations before income taxes and minority interest 7,081 21,933 Provision for income taxes 7,651 8,410 Minority interest
   2 - --------- --------- Income (loss) from continuing operations (572) 13,523 Income (loss) from discontinued operations,
   net 10,022 (4,200) --------- --------- Net income $ 9,450 $ 9,323 ========= ========= Basic earnings per common share Income
   (loss) from continuing operations $ (0.01) $ 0.14 Discontinued operations, net 0.12 (0.04) --------- --------- Net income
   $ 0.11 $ 0.10 ========= ========= Shares used in per share computation 89,590 94,730 ========= ========= Diluted earnings
   per common share Income (loss) from continuing operations $ (0.01) $ 0.14 Discontinued operations, net 0.12 (0.04) ---------
   --------- Net income $ 0.11 $ 0.10 ========= ========= Shares used in per share computation 89,590 96,019 ========= =========
   (a) Alliance revenue for the three months ended March 31, 2008 relates to ribavirin royalty of $12.8 million. Alliance revenue
   for the three months ended March 31, 2007 includes ribavirin royalties of $17.3 million and a $19.2 million milestone payment
   received from Schering- Plough related to the out-licensing of pradefovir. 

 Valeant Pharmaceuticals International
   Table 2 GAAP Reconciliation of Basic and Diluted Earnings Per Share For the Three Months Ended March 31, 2008 and 2007 Three
   Months Ended March 31, -------------------- (In thousands, except per share data) 2008 2007 --------- -------- Income (loss)
   from continuing operations $ (572) $13,523 Non-GAAP adjustments: Professional fees related to Special Committee option investigation
   (a) - 630 Restructuring, asset impairments and dispositions (b) (12,664) 7,238 Tax (c) 9,326 (828) --------- -------- Adjusted
   income (loss) from continuing operations before the above charges $ (3,910) $20,563 ========= ======== Adjusted basic EPS
   from continuing operations $ (0.04) $ 0.22 ========= ======== Adjusted diluted EPS from continuing operations $ (0.04) $ 0.21
   ========= ======== Shares used in adjusted basic per share calculation 89,590 94,730 ========= ======== Shares used in adjusted
   diluted per share calculation 89,590 96,019 ========= ======== (a) Non-recurring professional fees relating to the investigation
   by the Special Committee into stock option practices and the related restatement of financial statements. (b) Net restructuring,
   asset impairments and dispositions benefits for the three months ended March 31, 2008 of $12.7 million includes a $36.9 million
   net gain on the sale of Asia Pacific offset by other charges of $24.2 million, which included an impairment of $7.9 million
   relating to the sale of Argentina, $4.8 million of professional and legal fees and $11.5 million in employee related costs.
   Restructuring in March 31, 2007 relates to the restructuring announced in April 2006. (c) Tax effect for non-GAAP adjustments,
   including tax benefits from U.S. net operating losses not recognized for GAAP purposes. To supplement the consolidated financial
   results prepared in accordance with Generally Accepted Accounting Principles (GAAP), the company uses non-GAAP financial measures
   that exclude certain items, such as special charges and credits. Management does not consider the excluded items part of the
   day-to-day business or reflective of the core operational activities of the company as they result from transactions outside
   the ordinary course of business. Management uses non-GAAP financial measures internally for strategic decision making, forecasting
   future results and evaluating current performance. Guidance is provided only on a non-GAAP basis due to the inherent difficulty
   in forecasting such items. By disclosing non-GAAP financial measures, management intends to provide investors with a more
   meaningful, consistent comparison of the company's core operating results and trends for the periods presented. Non-GAAP financial
   measures are not prepared in accordance with GAAP; therefore, the information is not necessarily comparable to other companies
   and should be considered as a supplement to, not a substitute for, or superior to, the corresponding measures calculated in
   accordance with GAAP. 

 Valeant Pharmaceuticals International Table 3 Reconciliation of Consolidated Income From
   Operations to Non- GAAP Adjusted Earnings Before Interest, Taxes, Depreciation and Amortization ("EBITDA") For the Three Months
   Ended March 31, 2008 and 2007 (In thousands) Three Months Ended March 31, -------------------- 2008 2007 --------- --------
   Consolidated income from operations (GAAP) $ 15,106 $27,238 Depreciation and amortization 22,889 21,396 --------- --------
   EBITDA (non-GAAP) (a) 37,995 48,634 Other non-GAAP adjustments (b) (12,664) 7,868 --------- -------- Adjusted EBITDA (non-GAAP)
   (a) $ 25,331 $56,502 ========= ======== (a) We believe that EBITDA and Adjusted EBITDA are meaningful non-GAAP financial measures
   as earnings-derived indicators of the cash flow generation ability of the company. We calculate EBITDA by adding depreciation
   and amortization back to consolidated income from operations. Adjusted EBITDA excludes the additional costs set forth in note
   (b) below. EBITDA and Adjusted EBITDA, as defined and presented by us, may not be comparable to similar measures reported
   by other companies. (b) See Table 2 for explanation of non-GAAP adjustments. 

 Valeant Pharmaceuticals International
   Table 4 Supplemental Sales Information For the Three Months Ended March 31, 2008 and 2007 (In thousands) Three Months Ended
   % March 31, Increase/ ------------------ 2008 2007 (Decrease) --------- -------- ---------- Neurology Diastat(R) AcuDial(TM)
   $ 12,179 $ 11,072 10% Mestinon(R) 11,531 10,538 9% Cesamet(R) 9,996 5,911 69% Librax(R) 3,582 3,667 (2%) Migranal(R) 2,556
   3,036 (16%) Tasmar(R) 2,423 1,982 22% Dalmane(R)/Dalmadorm(R) 2,174 2,336 (7%) Zelapar(R) 1,939 195 894% Melleril 1,104 1,538
   (28%) Other Neurology 12,799 15,689 (18%) Dermatology Efudix/Efudex(R) 23,194 12,477 86% Kinerase(R) 5,610 8,378 (33%) Dermatix(TM)
   3,471 2,771 25% Oxsoralen-Ultra(R) 2,745 3,883 (29%) Other Dermatology 7,020 8,013 (12%) Infectious Disease Virazole(R) 5,496
   5,519 (0%) Other Infectious Disease 4,954 5,155 (4%) Other Therapeutic Classes Bisocard 6,825 4,694 45% Solcoseryl 6,285 5,347
   18% Bedoyecta(TM) 3,987 4,561 (13%) Nyal 2,388 1,763 35% MVI (multi-vitamin infusion) 2,258 2,482 (9%) Protamin 1,644 2,070
   (21%) Espaven 1,076 1,862 (42%) Other Pharmaceutical Products 44,677 42,994 4% --------- -------- Total product sales (a)
   $181,913 $167,933 8% ========= ======== (a) Product sales the three months ended March 31, 2008 include $1.1 million for products
   which have been divested in March 2008, compared to $4.1 million for the same period in 2007. 

 Valeant Pharmaceuticals
   International Table 5 Consolidated Condensed Statement of Revenue and Operating Income - Regional For the Three Months Ended
   March 31, 2008 and 2007 (In thousands) Three Months Ended March 31, ------------------- Revenues 2008 2007 % Change ---------
   --------- -------- North America $ 72,276 $ 62,599 15% International 29,151 35,275 -17% EMEA 80,486 70,059 15% --------- ---------
   Total specialty pharmaceuticals 181,913 167,933 8% Alliance revenue (including ribavirin royalties) (a) 12,773 36,470 -65%
   --------- --------- Consolidated revenues $194,686 $204,403 -5% ========= ========= Cost of goods sold $ 54,890 $ 46,901 17%
   ========= ========= Gross profit margin on pharmaceutical sales 70% 72% ========= ========= Three Months Ended March 31, -------------------
   Income from Operations 2008 2007 % Change --------- --------- -------- North America $ 27,413 $ 17,331 58% International (2,653)
   273 -- EMEA 11,087 18,709 -41% --------- --------- 35,847 36,313 -1% Corporate expenses $(15,427) $(15,960) -3% ---------
   --------- Total specialty pharmaceuticals 20,420 20,353 0% Restructuring, asset impairments and dispositions 12,664 (7,238)
   NM Research and development costs (17,978) 14,123 -- --------- --------- Total consolidated income from operations $ 15,106
   $ 27,238 ========= ========= 

 Three Months Ended March 31, ------------------------- Gross Profit 2008 % 2007 %
   -------- --- -------- --- North America $ 61,112 85% $ 52,797 84% International 17,618 60% 23,813 68% EMEA 48,293 60% 44,422
   63% -------- -------- Total specialty pharmaceuticals $127,023 70% $121,032 72% ======== ======== 

 (a) Alliance
   revenue for the three months ended March 31, 2008 relates to ribavirin royalty of $12.8 million. Alliance revenue for the
   three months ended March 31, 2007 includes ribavirin royalties of $17.3 million and a $19.2 million milestone payment received
   from Schering- Plough related to the out-licensing of pradefovir. 

 Valeant Pharmaceuticals International Table
   6 Consolidated Balance Sheet and Other Data (In thousands) As of As of March 31, December 31, Balance Sheet Data 2008 2007
   ----------- ------------ Cash and cash equivalents $498,097 $309,365 Marketable securities 21,162 52,122 ----------- ------------
   Total cash and marketable securities $519,259 $361,487 =========== ============ Accounts receivable, net $169,400 $191,796
   Inventory, net 118,199 115,177 Long-term debt 785,862 782,552 Three Months Ended Other Data March 31, --------------------------
   2008 2007 ----------- ------------ Cash flow provided by (used in): Operating activities $ 53,529 $ 31,107 Investing activities
   65,705 4,568 Financing activities and discontinued operations 59,892 (7,070) Effect of exchange rate changes on cash and cash
   equivalents 9,606 816 ----------- ------------ Net increase in cash and cash equivalents 188,732 29,421 Net decrease in marketable
   securities (30,960) (1,415) ----------- ------------ Net increase in cash and marketable securities $157,772 $ 28,006 ===========
   ============ 

 Valeant Pharmaceuticals International Table 7 Supplemental Non-GAAP Information on Currency Effect
   (In thousands) Three Months Ended March 31, -------------------- 2008 2007 --------- -------- Consolidated Product sales $181,913
   $167,933 Currency effect (13,983) Product sales, excluding currency impact $167,930 Operating income $ 15,106 $ 27,238 Currency
   effect (3,660) Operating income, excluding currency impact $ 11,446 Geographic Product Sales North America pharmaceuticals
   $ 72,276 $ 62,599 Currency effect (1,949) North America pharmaceuticals, excluding currency impact $ 70,327 International
   pharmaceuticals $ 29,151 $ 35,275 Currency effect (1,692) International pharmaceuticals, excluding currency impact $ 27,459
   EMEA pharmaceuticals $ 80,486 $ 70,059 Currency effect (10,342) EMEA pharmaceuticals, excluding currency impact $ 70,144 Note:
   Currency effect is determined by comparing adjusted 2008 reported amounts, calculated using 2007 monthly average exchange
   rates, to the actual 2007 reported amounts. Constant currency sales is not a GAAP-defined measure of revenue growth. Constant
   currency sales as defined and presented by us may not be comparable to similar measures reported by other companies. 

SOURCE: Valeant Pharmaceuticals International

Valeant Pharmaceuticals Laurie W. Little, 949-461-6002 laurie.little@valeant.com
   

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