AbbVie, Shire, Bank of America, Lakeland Industries and Petrobras are big market movers

Ecommerce Associated Press

Stocks that moved substantially or traded heavily Wednesday on the New York Stock Exchange and the Nasdaq Stock Market:

Continue Reading Below

NYSE

AbbVie Inc., up 50 cents to $54.63

The pharmaceutical company is reconsidering its $55 billion buyout of Shire, putting it at risk of paying a $1.6 billion fee.

Bank of America Corp., down 76 cents to $15.76

The bank reported a drop in quarterly profit because of a settlement over mortgage-backed securities with the U.S. government.

Continue Reading Below

KeyCorp, down 75 cents to $12.14

The regional bank reported a decline in third-quarter profit and revenue, which fell short of Wall Street expectations.

Petrobras SA, down $1.55 to $15.55

The Brazilian company was among battered oil stocks as the price of crude dropped after the International Energy Agency reduced its forecast for demand.

Nasdaq

Lakeland Industries Inc., up $2.17 to $23.60

Confirmation of a third case of Ebola in the U.S. and rising fear helped boost shares of the maker of protective and safety gear.

Republic Airways Holdings Inc., down 10 cents to $10.57

Airline stocks were hit after a health worker diagnosed with Ebola flew on a commercial flight, raising concerns the virus scare could curtail travel.

Orexigen Therapeutics Inc., up 52 cents to $3.98

The biotechnology company earned $100 million in milestone payments as the weight-loss drug Contrave is prepared for launch.

Shire PLC, down $75.08 to $170.49

The Ireland-based drug developer's potential buyer, AbbVie, is considering pulling out of the $55 billion deal.