Shares of some top biotechnology companies were up at the close of trading:

Amgen Inc. rose $1.20 or 1.0 percent, to $126.95.

Biogen Idec rose $3.45 or 1.1 percent, to $324.05.

Celgene Corp. rose $1.29 or 1.5 percent, to $86.51.

Gilead Sciences Inc. rose $.40 or .4 percent, to $92.45.