The second shift has been planned since the factory opened in 2008 but was put on hold amid the recession, according to the Associated Press, citing a plant spokeswoman.
The Japanese automaker currently makes about 100,000 cars a year at the Greensburg plant, which specializes in its popular Honda Civic sedan and the Honda Civic GX natural gas car. The additional staff will increase production to about 200,000 cars.
The announcement comes at a time when Honda continues to struggle amid low supplies since the March 11 earthquake and tsunami in Japan crippled supplier operations, forcing it to operate on reduced levels around the world.
While the automaker has predicted production volume at its North American assembly plants will return to normal in August, Honda warned the 2012 Civic will continue to operate at reduced levels until at least this fall.