LONDON -- European stock markets opened lower on Friday, with drugmaker Sanofi-Aventis SA down 4.8% after disappointing news on a cancer drug. Miners were also weaker across the board, as metals prices fell, with Xstrata PLC down 1.7% and BHP Billiton PLC down 1.3%. Autos were on the move with BMW AG up 2.2% after Goldman Sachs added it to its conviction buy list. Shares of Diageo PLC fell 1.9% after a downgrade from J.P. Morgan Cazenove. The Stoxx Europe 600 index fell 0.4% to 281.80, the German DAX 30 index was flat at 7,150.70, the French CAC 40 index fell 0.4% to 4,045.32 and the FTSE 100 index lost 0.5% to 5,934.30.

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